Document Type

Article

Publication Date

Winter 1-12-2025

Abstract

Objectives: To compare the remineralizing efficacy of (Fluoride (Fl) Varnish, Nanohydroxyapatite (n-HAp) serum and NovaMin-containing toothpaste) on premolars subjected to orthodontic debonding and a pH-cycling model. Methods: 60 human premolars were divided into six groups (n= 10). Group IA, sound enamel, IB, orthodontically treated premolars, IC, orthodontically treated premolars subjected to demineralization cycles. Three experimental groups included orthodontically treated premolars subjected to demineralization cycles and treated with Fl varnish (IIA), n-HAp serum (IIB), and NovaMin toothpaste (IIC). Surface topography and mineral content were evaluated using SEM-EDX analysis, and data were statistically analyzed using ANOVA test and Tukey’s post-hoc test. Results: SEM images of the experimental groups showed signs of surface precipitants and enamel prism reorganization. EDX analysis showed increased Ca and P where NovaMin recorded the highest Ca/P ratio followed by n-HAp serum, and then Fl varnish. Conclusions: NovaMin demonstrated the highest remineralization potential increasing Ca and P content. n-HAp serum exhibited comparable remineralization efficacy to NovaMin, while Fl varnish demonstrated the lowest remineralization potential.

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