Document Type

Book

Publication Date

Winter 1-1-2026

Abstract

Moringa oleifera has gained increasing attention for its diverse pharmacological properties, including its potential to modulate immune responses. This chapter explores the immunomodulatory potential of M. oleifera, exploring both its phytochemical composition and experimental evidence from in vitro and in vivo studies. Key bioactive constituents, such as flavonoids (quercetin, kaempferol, apigenin), phenolic acids (chlorogenic, ferulic, caffeic), glucosinolates (glucomoringin) and their hydrolysis product, benzyl isothiocyanate, are identified as contributors to its immune-regulating properties. It has been demonstrated that these substances affect cytokine expression, suppress pro-inflammatory mediators, increase phagocytic activity and alter lymphocyte reactions. In order to support the plant's traditional use as an immunomodulator, the chapter highlights the mechanistic insights into how moringa constituents affect immune pathways. The content presented lays a scientific foundation for future studies aimed at isolating and characterising specific compounds for therapeutic development. © 2027 selection and editorial matter, Nagendra Singh Chauhan, Durgesh Nandini Chauhan, Kamal Shah and Umesh Kumar Patil; individual chapters, the contributors.

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