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Aim: to evaluate the efficacy of immediate dentin sealing using universal adhesive in comparison to delayed dentin sealing in the reduction of the hypersensitivity in teeth prepared for indirect tooth composite restorations using Visual Analog Scale (VAS). Materials and methods: Fifty-four patients between 18 and 30 years of age were recruited and randomized to the treatment protocols. After baseline preoperative data collection, diagnosis of caries was done depending on the basis of clinical examination that was done tentatively and radiographic examination was done as well. After cavity preparation was done, for the cavities to be managed with immediate dentine sealing, the single bond universal adhesive was applied over all the dentinal surfaces according to the manufacturer’s instructions. For the cavities to be managed with delayed dentine sealing, no adhesive was applied on the dentinal surfaces and the impression was taken directly after cavity preparation using two-step technique. Hyper-Sensitivity was evaluated both intra-operatively (at baseline one day after the cavity preparation: by applying air from the triple way syringe directly over the prepared cavity and one week during temporization) and post operatively using (VAS). After try in and cementation of the indirect composite restoration post-cementation evaluation was done. (VAS) results were tabulated and statistically analyzed. Results: Delayed dentin sealing group (4.75) had a significantly higher median value of (VAS) than immediate dentin sealing group (0.32) (PConclusions: Inter-operative and post-cementation hypersensitivity problem after indirect resin composite restorations could be solved by using the immediate dentin sealing protocol using a self-etch adhesive.

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