Document Type

Article

Publication Date

5-2025

Abstract

Background Xerostomia is a common complaint among elderly patients. Due to the anti-inflammatory effect, Manuka honey could be a promising alternative remedy for many medical conditions, including xerostomia. The present study aimed to evaluate the effectiveness of Manuka honey oral rinse as a novel management for xerostomiain elderly patients. Methods This study was designed as a randomized, single-blinded clinical trial. 42 elderly patients who were allevaluated for the presence of xerostomia and hyposalivation were randomly allocated into 3 equal groups. The interventions were used 3 times per day for 1 month as follows: Manuka honey oral rinse in group I, natural honey honey oral rinse in group II, and saline in group III (control). The Summated Xerostomia Inventory (SXI) score, The Clinical Oral Dryness Score (CODS), and the salivary flow rate were evaluated for all groups at different intervals. The Oral Health Impact Profile (OHIP-14) questionnaire was assessed 1 month after the intervention. Results Manuka honey oral rinse caused a significant reduction of the subjective SXI score (2 ± 0.39) and objectiveclinical oral dryness (5.71 ± 0.91) scores compared to the other 2 groups. Moreover, the salivary flow rate wassignificantly higher after one month of using Manuka honey oral rinse (1.51 ± 0.34) than honey oral rinse group (1.01a ± 0.19), and the control group (0.81a ± 0.19). The most significant improvement of OHIP scores was seen in the Manuka honey group (5.50 ± 1.16) compared to the honey group (7.57a ± 1.02), and the control group (9.36ab ± 1.78).Conclusion Manuka honey oral rinse demonstrated high efficiency in the management of xerostomia among elderly patients when compared with natural honey as it relieved the symptoms and severity of xerostomia in the elderly along with a high rate of patient satisfaction.

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