objective: The purpose of this study is to compare the bone height and density around immediately loaded implants placed in the canine area supporting a mandibular overdenture in four different groups. The first group received low level laser therapy and antioxidants. The second group received antioxidants only. The third group received low level laser therapy only. The fourth group (control group) received no therapy. materials and methods: Following one stage surgical protocol twenty four implants were inserted bilaterally in the canine region to support mandibular overdentures for twelve completely edentulous patients in the form of two implants per patient. Patients were randomly divided into two equal groups. Group I received antioxidants in the form of vitamin C and E while group II did not receive antioxidants. Low level laser therapy was applied to the right side implant of both groups thus four groups each consisting of six implants were created. GroupI Right side: received low level laser therapy and antioxidants. Group I Left side: received antioxidants. GroupII Right side: received low level laser therapy. Group II Left side: received no therapy (control group). Ten days following the surgery the overdentures were inserted and once patients were comfortable to the prosthesis, they were placed on a zero, three, six and twelve months follow-up periods. Radiographic evaluation of peri-implant bony changes was made using cone beam computed tomography. Measurements were taken for bone density and crestal bone height surrounding the implants. Results: Regarding bone height and density there was no statistically difference between the groups which received Laser therapy: Laser and Antioxidant Therapy Group (Group I Right side) and the Laser Therapy Group (Group II Right side) which both showed more or less constant crestal bone height level and highest increase in bone density after twelve months follow-up period. There was statistically difference between these two groups and the two groups which did not receive laser therapy: Antioxidant Therapy Group (Group I Left side) and Control Group (Group II Left side) which both showed crestal bone height reduction and less increase in bone density after twelve months follow-up period. There was also statistically difference between the Antioxidant Therapy Group (Group I Left side) and the Control Group (Group II Left side) where the Control Group showed highest crestal bone height reduction and lowest increase in bone density after twelve months follow-up period. conclusions: Using low level laser therapy or antioxidants enhances osseointgration by improving crestal bone resorption and increasing bone density around immediately loaded implants supporting mandibular overdenture. laser therapy gives better results than antioxidants and combining antioxidants with laser therapy doesn’t differ than using laser therapy only however, using antioxidants gives better results than using no therapy.
Rizk, Fardos N. and Salah Eldin, Mouchira Prof., "Radiodensitometric Evaluation of the Effect of Low Energy Laser Irradiation With and Without Anioxidant Therapy on Immediately Loaded Implant Supported Overdenture" (2011). Dentistry. 87.