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natural products ranking in contemporary medicine is now well recognized and continues to be of interests as a source of novel lead compounds. Moreover, by applying molecular docking which is an effective approach to identify compounds that could conform to the site of interest of the target proteins. Thus, the potency of the compound is estimated by researchers and hence clinical application are achieved based on these biological discoveries. Accordingly, using the virtual screening based on natural product database could also be an encouraging approach for drug discovery, especially for complex diseases such as CVD

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