QSAR, pharmacophore modeling and molecular docking studies to identify structural alerts for some nitrogen heterocycles as dual inhibitor of telomerase reverse transcriptase and human telomeric G‑quadruplex DNA
Document Type
Article
Publication Date
Winter 11-27-2021
Abstract
Telomerase reverse transcriptase (TERT) and human telomeric G-quadruplex DNA are amongst the favorable target for researchers to discover novel and more effective anticancer agents. To understand and elucidate structure activity relationship and mechanism of inhibition of telomerase reverse transcriptase (TERT) and human telomeric G-quadruplex DNA, a QSAR modeling and molecular docking were conducted.
Recommended Citation
Jawarkar, R. D., Bakal, R. L., Khatale, P. N., Lewaa, I., Jain, C. M., Manwar, J. V., & Jaiswal, M. S. (2021). QSAR, pharmacophore modeling and molecular docking studies to identify structural alerts for some nitrogen heterocycles as dual inhibitor of telomerase reverse transcriptase and human telomeric G-quadruplex DNA. Future Journal of Pharmaceutical Sciences, 7(1), 231.