"Phytochemical and pharmacological studies on Lactuca sativa seed oil" by S. A. Said, H. A.E. Kashef et al.
 

Phytochemical and pharmacological studies on Lactuca sativa seed oil

Document Type

Article

Publication Date

7-27-1996

Abstract

The seed oil of L. sativa var. longifolia was chemically characterized. GLC revealed that the oil is built-up of oleic (61.5%), stearic (20.4), palmitic (9.7), myristic (2.8), cis-palmitoleic (1.2), behenic (0.5) and lignoseric (0.3) acids. β-Sitosterol and β-amyrin were identified by TLC. The oral LD50 of the oil in mice was found to be 19.8 ml/kg. The oil showed sedative effect in locomotor activity test, potentiation of the hypnotic effect of barbiturates, analgesic effect in acetic acid-induced writhing test and anticonvulsant activity against pentylenetetrazole-induced convulsion. The oil exhibits tolerance to its neurological effects on repeated use for prolonged time.

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