Metal‐and Catalyst‐Free Synthesis of 2‐Substituted‐Phthalimides Using 2‐(Arenesulfonyl) Phthalimide as Key Reagents

Document Type

Article

Publication Date

5-2-2023

Abstract

Phthalimide derivatives are important in medicinal chemistry, several phthalimidation methodologies have been developed. Here, we report a facile, metal-free, and catalyst-free method for the preparation of N-phthalimides in good to excellent yield by reacting 2-(arenesulfonyl)phthalimides with various amine substrates.

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