A highly selective and sensitive spectrofluorimetric method for the assessment of 3-nitrotyrosine in serum using (Eu(TTA)3Phen) photo probe

Authors

Ekram Hany Mohamed, The British University in EgyptFollow
Mohamed S. S. Attia, Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt
Ahmed O. Youssef, Analytical Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt
Nour El-Din A. Abdel-Sattar, Chemistry Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt
Mohammed A. Amin,, Department of Chemistry, Taif University, College of Science, Taif, 21944, Saudi Arabia
Sarah Alharthi, Department of Chemistry, Taif University, College of Science, Taif, 21944, Saudi Arabia
Safwat A. Mahmoud,, Physics Department, Faculty of Science, Northern Border University, Arar, Saudi Arabia
Mona N. Abou-Omar,, Department of Chemistry, Ain Shams University, Faculty of Women for Arts, Science and Education, Cairo, Egypt

Document Type

Article

Publication Date

Winter 2-3-2022

Abstract

A simple, accurate and fast method was developed for the assessment of 3-nitrotyrosine as a biomarker for the early diagnosis of liver cirrhosis with minimal hepatic encephalopathy (MHE) using a (Eu(TTA)3Phen) photo probe. 3-Nitrotyrosine can remarkably quench the luminescence intensity of the (Eu(TTA)3Phen) complex in DMSO at pH = 9 and λem = 617 nm. The quenching of the luminescence intensity of (Eu(TTA)3Phen) complex particularly the electrical emission band at λem = 617 nm is used for the assessment of 3-nitrotyrosine in different serum samples of patients with liver cirrhosis

Recommended Citation

Mohamed, Ekram Hany; Attia, Mohamed S. S.; Youssef, Ahmed O.; Abdel-Sattar, Nour El-Din A.; Amin,, Mohammed A.; Alharthi, Sarah; Mahmoud,, Safwat A.; and Abou-Omar,, Mona N., "A highly selective and sensitive spectrofluorimetric method for the assessment of 3-nitrotyrosine in serum using (Eu(TTA)3Phen) photo probe" (2022). Pharmacy. 703.
https://buescholar.bue.edu.eg/pharmacy/703