Submissions from 2018
A coumarin with an unusual structure from Cuphea ignea, its cytotoxicity and antioxidant activities, E. S. Moustafa, Noha Swilam, O. B. Ghanem, A. N. Hashim, M. A. Nawwar, U. Lindequist, and M. W. Linscheid
Different spectrophotometric methods for simultaneous determination of trelagliptin and its acid degradation product, Shereen Mowaka, Bassam M. Ayoub, Mostafa A. Hassan, and Wafaa A. Zaghary
A Replication Study for Association of LBX1 Locus With Adolescent Idiopathic Scoliosis in French-Canadian Population, Dina Nada, cedric Julien, Mark E. Samuels, and Alain Moreau
A replication study for association of LBX1 locus with adolescent idiopathic scoliosis in French-canadian population, Dina Nada, Cédric Julien, Mark E. Samuels, and Alain Moreau
Biochemistry of idiopathic scoliosis: From discovery to diagnostic biomarkers, Dina Nada and Alain Moreau
Biochemistry of Idiopathic Scoliosis: From Discovery to Diagnostic Biomarkers.Book; Pathogenesis of Idiopathic Scoliosis,, Dina Nada and Alain Moreau
Spray dried lactose based proniosomes as stable provesicular drug delivery carriers: Screening, formulation, and physicochemical characterization, Ali Nasr, Mona Qushawy, and Shady Swidan
Polyphenols LC-MS2 profile of Ajwa date fruit (Phoenix dactylifera L.) and their microemulsion: Potential impact on hepatic fibrosis, Khaled Nematallah, Nahla A. Ayoub, Essam Abdelsattar, Meselhy R. Meselhy, Mohamed M. Elmazar, Ahmed H. El-Khatib, Michael W. Linscheid, Rania M. Hathout, Kavitha Godugu, Aya Adel, and Shaker A. Mousa
Serum Vitamin D and Its Upregulated Protein, Thioredoxin Interacting Protein, Are Associated With Beta-Cell Dysfunction in Adult Patients With Type 1 and Type 2 Diabetes, Doaa F. Omar, Mohamed M. Kamal, Mohamed H. El-Hefnawy, and Hala Osman EL-Mesallamy
Mass spectrometric epitope mapping, Kwabena F.M. Opuni, Mahmoud Al-Majdoub, Yelena Yefremova, Reham F. El-Kased, Cornelia Koy, and Michael O. Glocker
Design, optimization and characterization of a transfersomal gel using miconazole nitrate for the treatment of candida skin infections, Mona Qushawy, Ali Nasr, Mohammed Abd-Alhaseeb, and Shady Swidan
The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats, Shereen N. Raafat, Reham M. Amin, Mohamed M. Elmazar, Mahmoud M. Khattab, and Aiman S. El-Khatib
A novel protocol for bacterial ghosts’ preparation using tween 80, Sameh Rabea, Mounir M. Salem-Bekhit, Fars K. Alanazi, Aymen S. Yassin, Nayera A. Moneib, and Abdel Gawad M. Hashem
Neurotherapeutic Effects of Bee Venom in a Rotenone-Induced Mouse Model of Parkinson’s Disease, M. K. Rakha, Rasha A. Tawfiq, R. A. Tawfiq, Mina Malak, M. A. Anwer, S. M. Salama, A. F. Mohamed, M. G. El-Hendy, Sh E. El-Said, N. M. Ahmed, K. S. Mekawi, A. M.Abd El-Aziz, and Mohamed M. Elmazar
UPLC/QTOF/MS profiling of two Psidium species and the in-vivo hepatoprotective activity of their nano-formulated liposomes, Fatema R. Saber, Ghada A. Abdelbary, Maha M. Salama, Dalia O. Saleh, Magda M. Fathy, and Fathy M. Soliman
The impact of seasonal variation on the volatile oil profile of leaves of Severinia buxifolia (Poir.) and its antimicrobial activity, Maha Salama, Mostafa Abdelkawy, Mohamed Saeed hifnawy, and Safaa Ahmed Nour
Polyphenols from Tamarix nilotica: LC–ESI-MSn profiling and in vivo antifibrotic activity, Ahmed Sekkien, Noha Swilam, Sherif S. Ebada, Ahmed Esmat, Ahmed H. El-Khatib, Michael W. Linscheid, and Abdel Nasser Singab
A Novel Role of Irbesartan in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats: Targeting DDAH/ADMA and EGFR/ERK Signaling, Nancy N. Shahin, Noha F. Abdelkader, and Marwa M. Safar
DOE, formulation, and optimization of Repaglinide nanostructured lipid carriers, Shady Swidan, Zeinab N. Mansour, Zeinab A. Mourad, Nahla A. Elhesaisy, Nada A. Mohamed, Mohamed S. Bekheet, Mohamed A. Badawy, Mai M. Elsemeiri, Aya E. Elrefaey, and Amera M. Hassaneen
Non-ionic surfactant based vesicular drug delivery system for topical delivery of caffeine for treatment of cellulite: design, formulation, characterization, histological anti-cellulite activity, and pharmacokinetic evaluation, Mahmoud H. Teaima, Sally A. Abdelhalim, Mohamed A. El-Nabarawi, Dalia Attia, and Doaa A. Helal
A Novel Role of a Chemotherapeutic Agent in a Rat Model of Endotoxemia: Modulation of the STAT-3 Signaling Pathway, Omnia S. Zaki, Marwa M. Safar, Afaf A. Ain-Shoka, and Laila A. Rashed
Bone Marrow Mesenchymal Stem Cells Combat Lipopolysaccharide-Induced Sepsis in Rats via Amendment of P38-MAPK Signaling Cascade, Omnia S. Zaki, Marwa M. Safar, Afaf A. Ain-Shoka, and Laila A. Rashed
Submissions from 2017
Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling, Shawqi H. Alawdi, Ezzeldin S. El-Denshary, Marwa M. Safar, Housam Eidi, Marie Odile David, and Mosaad A. Abdel-Wahhab
DOE Optimization of Nano-based Carrier of Pregabalin as Hydrogel: New Therapeutic &chemometric Approaches for Controlled Drug Delivery Systems, Mona Arafa and Bassam M. Ayoub
Nano-vesicles of salbutamol sulphate in metered dose inhalers: Formulation, characterization and in vitro evaluation, Mona Arafa and Bassam M. Ayoub
Economic evaluation of imipenem-cilastatin versus doripenem in ventilator-associated pneumonia in Egypt, Nermeen Ashoush
Review on pharmacokinetics of empagliflozin, an inhibitor of the sodium-glucose cotransporter-2, Nermeen Ashoush
Fluconazole-loaded solid lipid nanoparticles topical gel for treatment of pityriasis versicolor: formulation and clinical study, Dalia Attia, Shaimaa El-Housiny, Maii Atef Shams Eldeen, Yasmina Ahmed El-Attar, Hoda Salem, Ehab Bendas, and Mohamed El-Nabarawi
The FXR Agonist, Obeticholic Acid, Suppresses HCC Proliferation & Metastasis: Role of IL-6/STAT3 Signalling Pathway, Yasmeen M. Attia, Rasha A. Tawfiq, Aya A. Ali, and Mohamed M. Elmazar
Green pharmaceutical analysis of drugs coformulated with highly different concentrations using spiking and manipulation of their ratio spectra, Bassam M. Ayoub
Quantitative Analysis of Drugs with Highly Different Concentrations of Pharmaceutical Components Using Spectral Subtraction Techniques, Bassam M. Ayoub
Mean centering method for determination of empagliflozin and metformin, Bassam M. Ayoub, Rola M. Emam, Mahmoud M. Youssef, Muhammad N. El-Kattan, Marwa A. Sayed, Ahmed M. Kowider, Adly H. Seha, Engy A. Rabea, Rana M. Yakout, and Rolly H. Faried
LC-MS/MS determination of empagliflozin and metformin, Bassam M. Ayoub and Shereen Mowaka
Pharmacokinetic Evaluation of Empagliflozin in Healthy Egyptian Volunteers Using LC-MS/MS and Comparison with Other Ethnic Populations, Bassam M. Ayoub, Shereen Mowaka, Eman S. Elzanfaly, Nermeen Ashoush, Mohamed M. Elmazar, and Shaker A. Mousa
A validated HPLC method for simultaneous determination of perindopril arginine, amlodipine, and indapamide: Application in bulk and in different pharmaceutical dosage forms, Ramzia I. El-Bagary, Ehab F. Elkady, Shereen Mowaka, and Maria A. Attallah
Honey-based hydrogel: In vitro and comparative in vivo evaluation for burn wound healing, Reham F. El-Kased, Reham I. Amer, Dalia Attia, and Mohamed M. Elmazar
IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation, Sara M. Elkashef, An Ping Lin, Jamie Myers, Heinz Sill, Daifeng Jiang, Patricia L.M. Dahia, and Ricardo C.T. Aguiar
Rosmarinic acid attenuates hepatic fibrogenesis via suppression of hepatic stellate cell activation/proliferation and induction of apoptosis, Naglaa M. El-Lakkany, Walaa H. El-Maadawy, Sayed H. Seif el-Din, Olfat A. Hammam, Salwa H. Mohamed, Shahira M. Ezzat, Marwa M. Safar, and Samira Saleh
EVESOR, a model-based, multiparameter, Phase i trial to optimize the benefit/toxicity ratio of everolimus and sorafenib, Mévidette El-Madani, Olivier Colomban, Michel Tod, Denis Maillet, Julien Peron, Claire Rodriguez-Lafrasse, Osama A. Badary, Pierre Jean Valette, Thibaud Lefort, Philippe Cassier, Siham M. El-Shenawy, Ebtehal El-Demerdash, Juliette Hommel-Fontaine, Jerome Guitton, Marie Claude Gagnieu, Bassant M.M. Ibrahim, Catherine Barrois, Gilles Freyer, and Benoit You
Synthesis of new thieno[2,3-b]pyridine derivatives as pim-1 inhibitors, Hala B. El-Nassan and Bassem H. Naguib
Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides, Shahira M. Ezzat, Maha M. Salama, Engy A. Mahrous, Louis Maes, Cheol Ho Pan, and Essam Abdel-Sattar
Volatiles profiling in Ceratonia siliqua (Carob bean) from Egypt and in response to roasting as analyzed via solid-phase microextraction coupled to chemometrics, Mohamed A. Farag and Dina M. El-Kersh
Volatiles distribution in Nigella species (black cumin seeds) and in response to roasting as analyzed via solid-phase microextraction (SPME) coupled to chemometrics, Mohamed A. Farag, Dina M. El-Kersh, Dalia M. Rasheed, and Andreas G. Heiss
Advances in ligase chain reaction and ligation-based amplifications for genotyping assays: Detection and applications, Abdullah A.Y. Gibriel and Ola Adel
Biofilm formation in enterococci: Genotype-phenotype correlations and inhibition by vancomycin, Yomna Hashem, Heba M. Amin, Tamer M. Essam, Aymen S. Yassin, and Ramy K. Aziz
Telluric Acid Ameliorates Endotoxemic Kidney Injury in Mice: Involvement of TLR4, Nrf2, and PI3K/Akt Signaling Pathways, Ahmed F. Mohamed, Marwa M. Safar, Hala F. Zaki, and Helmy M. Sayed
Different applications of isosbestic points, normalized spectra and dual wavelength as powerful tools for resolution of multicomponent mixtures with severely overlapping spectra, Ekram Hany Mohamed, Hayam M. Lotfy, Maha A. Hegazy, and Shereen Mowaka
Comparative study between UHPLC-UV and UPLC-MS/MS methods for determination of alogliptin and metformin in their pharmaceutical combination, Shereen Mowaka and Bassam M. Ayoub
Enhanced LC-MS/MS determination of alogliptin and metformin in plasma: Application to a pharmacokinetic study, Shereen Mowaka, Ehab F. Elkady, Mohamed M. Elmazar, and Bassam M. Ayoub
Novel pure component contribution algorithm (PCCA) and UHPLC methods for separation and quantification of amlodipine, valsartan, and hydrochlorothiazide in ternary mixture, Shereen Mowaka, Maha A. Hegazy, Hayam M. Lotfy, and Ekram Hany Mohamed
A Concise Comparative Mini Review between HPLC-UV and Spectrophotometric Analysis of Gliptins in Pharmaceutical Formulations, Shereen Mowaka, Moataz S. Hendy, Mohamed M. Elmazar, Andrew Hakeem, Ramzia I. El-Bagary, Ehab F. Elkady, Mirna Antoun, Mai Shaalan, Sara Abdel-wahab, Mai Elsemeiri, Nourhan Abdelaziz, Alaa Mohamed, Menna Eltahawy, Asmaa Rashid, Rola Emam, Mahmoud Youssef, Muhammad El-kattan, Marwa Sayed, and Bassam M. Ayoub
Synthesis of New Pyridothienopyrimidinone and Pyridothieno -triazolopyrimidine Derivatives as Pim-1 Inhibitors, Bassem Naguib, Hala B. El-Nassan, and Engy A. Beshay
Synthesis of new pyridothienopyrimidinone derivatives as Pim-1 inhibitors, Bassem H. Naguib, Hala B. El-Nassan, and T. M. Abdelghany
Randomized double-blinded pilot clinical study of the antidiabetic activity of balanites aegyptiaca and uplc-esi-ms/ms identification of its metabolites, Hend Rashad, Fateheya M. Metwally, Shahira M. Ezzat, Maha M. Salama, Adel Hasheesh, and Amira Abdel Motaal
Association of serum pancreatic derived factor (PANDER) with beta-cell dysfunction in type 2 diabetes mellitus, Miral M. Shehata, Mohamed M. Kamal, Mohamed H. El-Hefnawy, and Hala O. EL-Mesallamy
Ischemia-responsive protein 94 is a key mediator of ischemic neuronal injury-induced microglial activation, Rajiv Tikamdas, Sarthak Singhal, Ping Zhang, Justin A. Smith, Eric G. Krause, Stanley M. Stevens, Sihong Song, and Bin Liu
Mass spectrometric characterization of protein structures and protein complexes in condensed and gas phase, Yelena Yefremova, Bright D. Danquah, Kwabena F.M. Opuni, Reham F. El-Kased, Cornelia Koy, and Michael O. Glocker
Anti-tumor efficacy of an integrated methyl dihydrojasmonate transdermal microemulsion system targeting breast cancer cells: In vitro and in vivo studies, Rania Yehia, Rania M. Hathout, Dalia A. Attia, Mohamed M. Elmazar, and Nahed D. Mortada
Comparative study between different simple methods manipulating ratio spectra for the analysis of alogliptin and metformin co-formulated with highly different concentrations, Wafaa A. Zaghary, Shereen Mowaka, Mostafa A. Hassan, and Bassam M. Ayoub
Suitability of various chromatographic and spectroscopic techniques for analysis and kinetic degradation study of trelagliptin, Wafaa A. Zaghary, Shereen Mowaka, Mostafa A. Hassan, and Bassam M. Ayoub
Comparative liquid chromatographic study for concurrent determination of canagliflozin and metformin in combined tablets, Wafaa A. Zaghary, Shereen Mowaka, and Moataz S. Hendy
Submissions from 2016
Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations, Noha F. Abdelkader, Marwa M. Safar, and Hesham A. Salem
Indole-3-carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study, Mai M. Abdelmageed, Reem N. El-Naga, Ebtehal El-Demerdash, and Mohamed M. Elmazar
Glucosinolates profile, volatile constituents, antimicrobial, and cytotoxic activities of Lobularia libyca, Amal A. Al-Gendy, Khaled A. Nematallah, Soumaya S. Zaghloul, and Nahla A. Ayoub
Mini-review and comparative study: preparation and evaluation of nicotine-loaded buccal mucoadhesive tablets/films designed for smoking cessation, Mona Arafa and Bassam M. Ayoub
Polyphenols from Erythrina crista-galli: Structures, molecular docking and phytoestrogenic activity, Naglaa S. Ashmawy, Mohamed L. Ashour, Michael Wink, Mohamed El-Shazly, Fang Rong Chang, Noha Swilam, Ashraf B. Abdel-Naim, and Nahla Ayoub
Mini-review: Pharmacokinetics of omarigliptin, a once-weekly dipeptidyl peptidase-4 inhibitor, Nermeen Ashoush
Enhancement of plasma extraction recovery of empagliflozin and metformin combination using liquid-liquid extraction and vacuum evaporation techniques, Bassam M. Ayoub
Linagliptin: A concise review on analytical and bio-analytical methods, Bassam M. Ayoub
Mini-review: Analytical procedures for alogliptin determination in biological fluids and pharmaceutical formulations, Bassam M. Ayoub
A guide for using experimental design in chromatographic method development: Applied to the analysis of selected anti-diabetic pharmaceutical combinations, Bassam M. Ayoub and O. Abdel-Aziz
Review of HPLC/UPLC-UV methods for sensitive determination of nicotine in plasma, Bassam M. Ayoub, Mona Arafa, and Moataz S. Hendy
Economic Evaluation of the Combined Use of Warfarin and Low-dose Aspirin Versus Warfarin Alone in Mechanical Valve Prostheses, Manal H. El-Hamamsy, Gihan H. Elsisi, Randa Eldessouki, Mohamed M. Elmazar, Ahmed S. Taha, Basma F. Awad, and Hossam Elmansy
Natural antibacterial remedy for respiratory tract infections, Reham F. El-Kased
Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment, Sara M. Elkashef, Simon J. Allison, Maria Sadiq, Haneen A. Basheer, Goreti Ribeiro Morais, Paul M. Loadman, Klaus Pors, and Robert A. Falconer
An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity, Sara M. Elkashef, Mark Sutherland, Laurence H. Patterson, Paul M. Loadman, and Robert A. Falconer
Cytotoxicity and Chemical Investigation of the Aerial Parts of Markhamia zanzibarica (Bojer Ex Dc.) K. Schum. (Bignoniaceae), Dina M. El-Kersh, Riham S. El Dine, Dina R. Abou-Hussein, Fatma S. El-Sakhawy, and Mohamed M. Elmazar
Use of random amplified polymorphic DNA (RAPD) technique to study the genetic diversity of eight aloe species, Shahira M. Ezzat, Abeer M. El Sayed, and Maha M. Salama
HPLC–DAD–MS/MS profiling of standardized rosemary extract and enhancement of its anti-wrinkle activity by encapsulation in elastic nanovesicles, Shahira M. Ezzat, Maha M. Salama, Aliaa N. ElMeshad, Mahmoud H. Teaima, and Laila A. Rashad
Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces, Shahira M. Ezzat, Maha M. Salama, Sayed H. Seif el-Din, Samira Saleh, Naglaa M. El-Lakkany, Olfat A. Hammam, Maha B. Salem, and Sanaa S. Botros
Anti-acetylcholinesterase potential and metabolome classification of 4 Ocimum species as determined via UPLC/qTOF/MS and chemometric tools, M. A. Farag, S. M. Ezzat, Maha M. Salama, and M. G. Tadros
Anti-acetylcholinesterase activity of essential oils and their major constituents from four Ocimum species, Mohamed A. Farag, Shahira M. Ezzat, Maha M. Salama, Mariane G. Tadros, and Rabah A.T. Serya
Square wave voltammetric determination of rasagiline mesylate on hanging mercury drop electrode and its application in dosage form and biological fluids, Ibrahim H.I. Habib, Mohamed Rizk, Dalia Mohamed, Shereen Mowaka, and Rasha Th El-Eryan
Wharton's jelly-derived mesenchymal stem cells combined with praziquantel as a potential therapy for Schistosoma mansoni-induced liver fibrosis, Olfat A. Hammam, Nagwa Elkhafif, Yasmeen M. Attia, Mohamed T. Mansour, Mohamed M. Elmazar, Rania M. Abdelsalam, Sanaa A. Kenawy, and Aiman S. El-Khatib
Beta vulgaris subspecies cicla var. flavescens (Swiss chard): Flavonoids, hepatoprotective and hypolipidemic activities, A. N. Hashem, M. S. Soliman, M. A. Hamed, Noha Swilam, U. Lindequist, and M. A. Nawwar
17β-Estradiol augments antidepressant efficacy of escitalopram in ovariectomized rats: Neuroprotective and serotonin reuptake transporter modulatory effects, Weam W. Ibrahim, Marwa M. Safar, Mahmoud M. Khattab, and Azza M. Agha
Association of expression levels of pluripotency/stem cell markers with the differentiation outcome of Wharton's jelly mesenchymal stem cells into insulin producing cells, Dina H. Kassem, Mohamed M. Kamal, Abd El Latif G. El-Kholy, and Hala O. El-Mesallamy
Exendin-4 enhances the differentiation of Wharton's jelly mesenchymal stem cells into insulin-producing cells through activation of various β-cell markers, Dina H. Kassem, Mohamed M. Kamal, Abd El Latif G. El-Kholy, and Hala O. El-Mesallamy
Structural Docking Studies of COX-II Inhibitory Activity for Metabolites Derived from Corchorus olitorius and Vitis vinifera, Yasmine Mandour, Heba Handoussa, Noha Swilam, Rasha Hanafi, and Laila Mahran
Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5′-Triphosphate, Gregory D. McCluskey, Samy Mohamady, Scott D. Taylor, and Stephen L. Bearne
One flask synthesis of 2′,3′-cyclic nucleoside monophosphates from unprotected nucleosides using activated cyclic trimetaphosphate, Samy Mohamady and Scott D. Taylor
Synthesis of Nucleoside Triphosphates from 2′-3′-Protected Nucleosides Using Trimetaphosphate, Samy Mohamady and Scott D. Taylor
Phenolic profiling of an extract from Eugenia jambos L. (Alston) - The structure of three flavonoid glycosides - Antioxidant and cytotoxic activities, Mahmoud A. Nawwar, A. N. Hashem, S. A. Hussein, Noha Swilam, A. Becker, B. Haertel, U. Lindequist, A. El-Khatib, and M. W. Linscheid
Bone Marrow-Derived Endothelial Progenitor Cells Protect Against Scopolamine-Induced Alzheimer-Like Pathological Aberrations, Marwa M. Safar, Hany H. Arab, Sherine M. Rizk, and Shohda A. El-Maraghy
Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1), Riham Soliman Said, Ebtehal El-Demerdash, Ahmed Shafik Nada, and Mohamed M. Kamal
Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces, Maha Salama, Shahira Mohammed Ezzat, and Samira Saleh
Identification of phenolic secondary metabolites from Schotia brachypetala Sond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans, Mansour Sobeh, Esraa ElHawary, Herbenya Peixoto, Rola M. Labib, Heba Handoussa, Noha Swilam, Ahmed H. El-Khatib, Farukh Sharapov, Tamer Mohamed, Sonja Krstin, Michael W. Linscheid, Abdel Nasser Singab, Michael Wink, and Nahla Ayoub
Identification of Suitable Endogenous Normalizers for qRT-PCR Analysis of Plasma microRNA Expression in Essential Hypertension, Mohamed Hassan M. Solayman, Taimour Langaee, Archanakumari Patel, Lamia El-Wakeel, Manal El-Hamamsy, Osama A. Badary, and Julie A. Johnson