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Submissions from 2005

Naringenin attenuates cisplatin nephrotoxicity in rats, Osama A. Badary, Sahar Abdel-Maksoud, Wafaa A. Ahmed, and Gehan H. Owieda

Serotonin glucuronidation by Ah receptor- and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells, Christoph Köhle, Osama A. Badary, Karl Nill, Barbara S. Bock-Hennig, and Karl Walter Bock

An improved method for the synthesis of nucleoside triphosphate analogues, Samy Mohamady and David L. Jakeman

Submissions from 2004

Microbial side-chain degradation of progesterone II. Application of different techniques for progesterone conversion by Fusarium dimerium, Nehad Z. Adham, Osama M. El-Tayeb, Abdel Gawad M. Hashem, Heba El-Refai, and Lotfy A. Sallam

Cardiac DT-diaphorase contributes to the detoxification system against doxorubicin-induced positive inotropic effects in guinea-pig isolated atria, Osama A. Badary, Azza S. Awad, Sahar Abdel-Maksoud, and Farid M.A. Hamada

Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands, Mohamed M. Elmazar and H. Nau

Submissions from 2003

Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe, S. M. Attia, U. Kliesch, G. Schriever-Schwemmer, Osama A. Badary, F. M. Hamada, and I. D. Adler

Effects of benzo[a]pyrene on tissue activities of metabolizing enzymes and antioxidant system in normal and protein-malnourished rats, Osama A. Badary, Hanan M. AbdEl-Gawad, Ragia A. Taha, Azza A. Ali, and Farid M.A. Hamada

Thymoquinone is a potent superoxide anion scavenger, Osama A. Badary, Ragia A. Taha, Ayman M. Gamal El-Din, and Mohamed H. Abdel-Wahab

Goitrogenic activity of p-coumaric acid in rats, Fatima Khelifi-Touhami, Ragia A. Taha, Osama A. Badary, Alkassem Lezzar, and Farid M.A. Hamada

Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians, Christoph Köhle, Bernd Möhrle, Peter A. Münzel, Matthias Schwab, Dorothee Wernet, Osama A. Badary, and Karl Walter Bock

A new approach for the treatment of malignant melanoma: Enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2, Ahmed M. Mansour, Joachim Drevs, Norbert Esser, Farid M. Hamada, Osama A. Badary, Clemens Unger, Iduna Fichtner, and Felix Kratz

Ultraviolet Spectrophotometric Determination of Primary Amine-Containing Drugs via Their Charge-Transfer Complexes with Tetracyanoethylene, Mohamed S. Rizk, Safaa S. Toubar, Maha A. Sultan, and Shereen H. Assaad

Submissions from 2002

Microbial side-chain degradation of progesterone I: Optimization of the transformation conditions, Nehad Z. Adham, Osama M. El-Tayeb, Abdel Gawad M. Hashem, Heba A. El-Refai, and Lotfy A. Sallam

Prevention of vitamin A teratogenesis by phytol or phytanic acid results from reduced metabolism of retinol to the teratogenic metabolite, all-trans-retinoic acid, Thomas Arnhold, Mohamed M. Elmazar, and Heinz Nau

Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: studies with topoisomerase II inhibitors, S. M. Attia, T. E. Schmid, Osama A. Badary, F. M. Hamada, and I-D Adler

Effect of bioadhesive polymers, sodium salicylate, polyoxyethylene-9-lauryl ether, and method of preparation on the relative hypoglycemia produced by insulin enteric-coated capsules in diabetic beagle dogs, E. A. Hosny, H. I. Al-Shora, and Mohamed M. Elmazar

Oral delivery of insulin from enteric-coated capsules containing sodium salicylate: Effect on relative hypoglycemia of diabetic beagle dogs, Ehab A. Hosny, Hassan I. Al-Shora, and Mohamed M. Elmazar

Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers, Salama A. Salama, William W. Au, Glenn C. Hunter, Richard G. Sheahan, Osama A. Badary, Ashraf B. Abdel-Naim, and Farid M.A. Hamada

Submissions from 2001

Relative hypoglycemic effect of insulin suppositories in diabetic beagle dogs: Optimization of various concentrations of sodium salicylate and polyoxyethylene-9-lauryl ether, Ehab Ahmed Hosny, Hasan Ibrahim Al-Shora, and Mohamad Mohey Aldin Elmazar

Cytogenetic assays for monitoring populations exposed to environmental mutagens, William W. Au, Osama A. Badary, and Moon Y. Heo

Inhibitory effects of thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis., Osama A. Badary and A. M. Gamal El-Din

Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARα- or RARγ-selective agonist with a RXR-selective agonist, Mohamed M. Elmazar, Ralph Rühl, and Heinz Nau

Effect of different bile salts on the relative hypoglycemia of Witepsol W35 suppositories containing insulin in diabetic beagle dogs, E. A. Hosny, H. I. Al-Shora, and Mohamed M. Elmazar

Embryonic subcellular distribution of 13-cis- and all-trans-retinoic acid indicates differential cytosolic/nuclear localization, Ralph Rühl, Claudi Plum, Mohamed M. Elmazar, and Heinz Nau

Submissions from 2000

Effect of streptozotocin-induced hyperglycaemia on intravenous pharmacokinetics and acute cardiotoxicity of doxorubicin in rats, Othman A. Al-Shabanah, Hassan A. El-Kashef, Osama A. Badary, Abdulla M. Al-Bekairi, and Mohamed M. Elmazar

Selective agonists of retinoic acid receptors: Comparative toxicokinetics and embryonic exposure, Husam M.M. Arafa, Mohamed M. Elmazar, Farid M.A. Hamada, Uwe Reichert, Braham Shroot, and Heinz Nau

The influence of thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats, Osama A. Badary, Ashraf B. Abdel-Naim, Mohamed H. Abdel-Wahab, and Farid M.A. Hamada

Differential alteration of cisplatin cytotoxicity and myelotoxicity by the paclitaxel vehicle cremophor EL, Osama A. Badary, Ashraf B. Abdel-Naim, Amani E. Khalifa, and Farid M.A. Hamada

Antitumor activity of thymoquinone against fibrosarcoma tumorigenesis, Osama A. Badary and A. M. Gamal El-Din

Evaluation of cisplatin combined with ondansetron in Ehrlich ascites carcinoma in vitro and in vivo, Osama A. Badary, Sahar Moustafa Sharaby, Sanaa Abd El Baky Kenawy, Ezz El Deen El-Denshary, and Farid Mohamed Ahmed Hamada

Submissions from 1999

The protective action of thymol against carbon tetrachloride hepatotoxicity in mice, K. Alam, M. N. Nagi, Osama A. Badary, O. A. Al-Shabanah, A. C. Al-Rikabi, and A. M. Al-Bekairi

Synthesis and anticonvulsant activity of some 1-substituted-2- oxopyrrolidine derivatives, II, Abdulrahman M. Al-Obaid, Hussein I. El-Subbagh, Othman A. Al-Shabanah, and Mohamed M. Elmazar

Enhanced generation of leukotriene B4 and superoxide radical from calcium ionophore (A23187) stimulated human neutrophils after priming with interferon-alpha, O. A. Al-Shabanah, M. A. Mansour, and Mohamed M. Elmazar

L-histidinol attenuates Fanconi syndrome induced by ifosfamide in rats, Osama A. Badary

Prospects for drug treatment of AIDS, Osama A. Badary

Thymoquinone attenuates ifosfamide-induced Fanconi syndrome in rats and enhances its antitumor activity in mice, Osama A. Badary

Inhibition of benzo(a)pyrene-induced forestomach carcinogenesis in mice by thymoquinone, Osama A. Badary, O. A. Al-Shabanah, M. N. Nagi, A. C. Al-Rikabi, and Mohamed M. Elmazar

Effect of adenosine on pulmonary circulation of rabbits, Hassan El-Kashef, Mohamed M. Elmazar, Othman A. Al-Shabanah, and Abdullah M. Al-Bekairi

Effect of bromocriptine on uterine contractility in near-term pregnant rats, A. M. Moustafa, E. M. El-Sayed, Osama A. Badary, A. M. Mansour, and F. M.A. Hamada

Thymoquinone protects against carbon tetrachloride hepatotoxicity in mice via an antioxidant mechanism, Mahmoud N. Nagi, Khurshid Alam, Osama A. Badary, Othman A. Al-Shabanah, Hussein A. Al-Sawaf, and Abdullah M. Al-Bekairi

Metabolism of retinaldehyde isomers in pregnant rats: 13-cis- and all- trans-retinaldehyde, but not 9-cis-retinaldehyde, yield very similar patterns of retinoid metabolites, Jörn Oliver Sass, Georg Tzimas, Mohamed M. Elmazar, and Heinz Nau

Submissions from 1998

Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity, O. A. Al-Shabanah, Osama A. Badary, M. N. Nagi, N. M. Al-Gharably, A. C. Al-Rikabi, and A. M. Al-Bekairi

Effects of L-histidinol on the antitumour activity and acute cardiotoxicity of doxorubicin in mice, Othman A. Al-Shabanah, Osama A. Badary, Naji M. Al-Gharably, and Hussein A. Al-Sawaf

Taurine attenuates fanconi syndrome induced by ifosfamide without compromising its antitumor activity, Osama A. Badary

Effect of Cremophor EL on the pharmacokinetics, antitumor activity and toxicity of doxorubicin in mice, Osama A. Badary, Othman A. Al-Shabanah, Naji M. Al-Gharably, and Mohamed M. Elmazar

Acute and subchronic toxicity of thymoquinone in mice, Osama A. Badary, Othman A. Al-Shabanah, Mahmoud N. Nagi, Abdullah M. Al-Bekairi, and Mohamed M. Elmazar

Effects of Ehrlich Ascites Carcinoma cells on the responses of non- pregnant and pregnant uterine smooth muscles of mice to oxytocin and acetylcholine, H. A. El-Kashef, Osama A. Badary, Mohamed M. Elmazar, O. Al-Shabana, and A. Al-Bekiri

Hypoglycemic effect of oral insulin in diabetic rabbits using pH-dependent coated capsules containing sodium salicylate without and with sodium cholate, E. A. Hosny, N. M. Khan Ghilzai, T. A. Al-Najar, and Mohamed M. Elmazar

Effect of deoxycholic acid, polycarbophil or both on the relative hypoglycemia of rectal insulin suppositories containing sodium salicylate in diabetic rabbits, Ehab A. Hosny, Naushad M. Khan Ghilzai, and Mohamed M. Elmazar

Submissions from 1997

Synthesis and pharmacological evaluation of some 3-[(4-aryl and benzylpiperazinyl) alkoxy]-2-methyl-4-(3H)-quinazolinones as potential neuroleptic agents, Ashraf H. Abadi, Hamad A. Al-Khamees, Omar A. Al-Deeb, Mohamed M. Elmazar, and Abdulrahman M. Ageel

Protective effect of thymoquinone against carbon tetrachloride- induced hepatotoxicity in mice, N. M. Al-Gharably, Osama A. Badary, M. N. Nagi, O. A. Al-Shabanah, H. A. Al-Sawaf, A. C. Al-Rikabi, and A. M. Al-Bekairi

Effect of L-Histidinol on cisplatin nephrotoxicity in the rat, Osama A. Badary, Mahmoud N. Nagi, Hussein A. Al-Sawaf, Mohammed Al-Harbi, and Abdullah M. Al-Bekairi

Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity, Osama A. Badary, Mahmoud N. Nagi, Othman A. Al-Shabanah, Hussain A. Al-Sawaf, Mohammed O. Al-Sohaibani, and Abdullah M. Al-Bekairi

Toward the mechanism of valproate teratogenesis: Structural basis and interactions with agents that alter folate metabolism, Mohamed M. Elmazar and H. Nau

RARα-mediated teratogenicity in mice is potentiated by an RXR agonist and reduced by an RAR antagonist: Dissection of retinoid receptor-induced pathways, Mohamed M. Elmazar, Ralph Rühl, Uwe Reichert, Braham Shroot, and Heinz Nau

Evaluation of hepatotoxicity in rats of four synthetic valproic acid derivatives with potential anticonvulsant activity and low teratogenicity, Mohamed M. Elmazar, S. A. Said, H. A. Salim, and H. A. Ghoneim

Heterogeneity of the mechanisms underlying activation of adenylate cyclase by endothelin-1 in rabbit and bovine iris sphincter and tracheal smooth muscles, Abdalla M. El-Mowafy, Mohamed M. Elmazar, Ahmed M. Rabea, Mamdouh M. El-Shishtawy, and Ata A. Abdel-Latif

Isolation of hypotensive flavonoids from chenopodium species growing in egypt, Ahmed A. Gohar and Mohamed M. Elmazar

Promotion of oral insulin absorption in diabetic rabbits using pH-dependent coated capsules containing sodium cholate, Ehab A. Hosny, Naushad M.Khan Ghilzai, and Mohamed M. Elmazar

Submissions from 1996

Nadolol-glibenclamide interaction: Relevance to carbohydrate metabolism in hyperglycaemic rats, A. H. Abdel Aziz, A. M. Moustafa, M. F. Abd Ellah, and Mohamed M. Elmazar

Long-term preventive regimen of tamoxifen and recombinant human interferon α2b on dimethylbenz (a) anthracene, A. M. Agha, Osama A. Badary, A. G. El-Din, Y. Hafez, and O. El-Ahmady

5-Substituted-2-thiohydantoin analogs as a novel class of antitumor agents, A. M. Al-Obaid, H. I. El-Subbagh, Al Khodair, and Mohamed M. Elmazar

Fully automated determination of selective retinoic acid receptor ligands in mouse plasma and tissue by reversed-phase liquid chromatography coupled on-line with solid-phase extraction, H. M.M. Arafa, F. M.A. Hamada, Mohamed M. Elmazar, and H. Nau

Altered uterine sensitivity to oxytocin and prostaglandin F(2α), in dimethylbenz(a)anthracene (DMBA)-induced rat mammary carcinoma: The effects of tamoxifen and/or recombinant human interferon α2b therapy, Osama A. Badary, Azza M. Agha, El Sayed M. El-Sayed, and Farid M.A. Hamada

Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect, Ursula Bojic, Mohamed M. Elmazar, Ralf Siegbert Hauck, and Heinz Nau

Methionine reduces the valproic acid-induced spina bifida rate in mice without altering valproic acid kinetics, Katharine Ehlers, Mohamed M. Elmazar, and Heinz Nau

Effect of praziquantel on serum glucose and insulin levels in normal and hyperglycemic rats, Hassan A. El-Kashef, Hatem A. Salem, Shehta A. Said, and Mohamed M. Elmazar

Pattern of retinoid-induced teratogenic effects: Possible relationship with relative selectivity for nuclear retinoid receptors RARα, RARβ, and RARγ, Mohamed M. Elmazar, U. Reichert, B. Shroot, and H. Nau

Does tissue polypeptide-specific antigen (TPS) relate to tissue polypeptide antigen (TPA) in Ehrlich ascites carcinoma (EAC)-bearing mice?, A. B. Halim, O. El-Ahmady, Sanaa Eissa, Osama A. Badary, Azza Agha, and P. Oehr

The effect of aspartame on seizure susceptibility and the anticonvulsant action of ethosuximide, valproate and phenytoin in mice, N. Y. Helali, H. El-Kashef, H. Salem, N. Gamiel, and Mohamed M. Elmazar

All-trans-retinoyl-β-glucuronide is a potent teratogen in the mouse because of extensive metabolism to all-trans-retinoic acid, H. Nau, Mohamed M. Elmazar, R. Rühl, R. Thiel, and J. O. Sass

Phytochemical and pharmacological studies on Lactuca sativa seed oil, S. A. Said, H. A.E. Kashef, M. M.E. Mazar, and O. Salama

Submissions from 1995

Effect of zinc on the anti-inflammatory and ulcerogenic activities of indometacin and diclofenac, Gamal Abou-Mohamed, Hassan A. El-Kashef, Hatem A. Salem, and Mohamed M. Elmazar

Interferon enhancement of tamoxifen efficacy in Ehrlich ascites carcinoma: A follow-up study of tissue polypeptide antigen, Osama A. Badary, A. M. Agha, A. B. Halim, and O. El-Ahmady

Ethanol potentiates valproic acid-induced neural tube defects (NTDs) in mice due to toxicokinetic interactions, Mohamed M. Elmazar and Heinz Nau

Submissions from 1994

Interactions of a novel catecholamine, GP-2-128, with adrenoceptors, G. Abou-Mohamed, R. W. Caldwell, G. O. Carrier, Mohamed M. Elmazar, and R. R. Tuttie

Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13- dicis-retinoic acid to the mouse and rat embryos, G. Tzimas, J. O. Sass, W. Wittfoht, Mohamed M. Elmazar, K. Ehlers, and H. Nau

Submissions from 1993

Anticonvulsant and neurotoxic activities of twelve analogues of valproic acid, Mohamed M. Elmazar, R. ‐S Hauck, and H. Nau

Trimethoprim potentiates valproic acid-induced Neural Tube Defects (NTDs) in mice, Mohamed M. Elmazar and Heinz Nau

Submissions from 1992

Methotrexate increases valproic acid‐induced developmental toxicity, in particular neural tube defects in mice, Mohamed M. Elmazar and H. Nau

Effect of supplementation with folinic acid, vitamin B6, and vitamin B12 on valproic acid-induced teratogenesis in mice, Mohamed M. Elmazar, Renate Thiel, and Heinz Nau

The enantioselective teratogenicity of 2-n-propyl-4-pentynoic acid (4-yn-VPA) is due to stereoselective intrinsic activity and not differences in pharmacokinetics, R. S. Hauck, Mohamed M. Elmazar, C. Plum, and H. Nau

Submissions from 1991

On the development of alternative antiepileptic drugs - Lack of Enantioselectivity of the Anticonvulsant Activity, in Contrast to Teratogenicity, of 2-n-Propyl-4-pentenoic Acid and 2-n-Propyl-4-pentynoic Acid, Analogues of the Anticonvulsant Drug Valproic Acid, R. S. Hauck, H. Nau, and Mohamed M. Elmazar

Submissions from 1989

Maternal factors influencing development of embryos from mice superovulated with gonadotropins, Mohamed M. Elmazar, R. Vogel, and H. Spielmann

Radiation exposure and the effect of piroxicam and diclofenac on mediator release from isolated guinea-pig lung, M. T. Khayyal, H. Roushdy, S. Saleh, M. El-Ghazaly, S. Kenawy, and M. A. El Mazar

Submissions from 1988

Amniotic fluid cholinesterase of valproate-induced exencephaly in the mouse: an animal model for prenatal diagnosis of neural tube defects, Mohamed M. Elmazar, Richard Vogel, and Horst Spielmann

Submissions from 1982

Studies on the teratogenic effects of different oral preparations of caffeine in mice, Mohamed M. Elmazar, Patricia R. McElhatton, and Frank M. Sullivan

The effect of prenatal phenytoin administration on neonatal brain tryptophan metabolism, Mohamed M. Elmazar and F. M. Sullivan

Teratogenic effects of caffeine in mice: The role of reduced food and water intake, P. R. McElhatton, Mohamed M. Elmazar, and F. M. Sullivan

Submissions from 1981

Acute Studies to Investigate the Mechanism of Action of Caffeine as a Teratogen in Mice, Mohamed M. Elmazar, Patricia R. McElhatton, and F. M. Sullivan

Effect of prenatal phenytoin administration on postnatal development of the rat: A behavioral teratology study, Mohamed M. Elmazar and F. M. Sullivan

Submissions from 1980

Effect of prenatal Phenytoin administration on brain tryptophan metabolism of rat offspring during the preweaning period, Mohamed M. Elmazar and F. M. SULLIVAN

Submissions from 1977

Effect of prenatal phenytoin treatment on postnatal development, M. M. Ata and F. M. Sullivan

Action of oral contraceptive drugs on protein metabolism in rats., M. T. Khayyal, M. E. el-Sayed, H. M. Ahmed, and M. A. Ata

Effect of oral contraceptive drugs on carbohydrate metabolism in alloxan diabetic rats., M. T. Khayyal, M. E. el-Sayed, H. M. Ahmed, and M. M. Ata

Submissions from 1975

Pharmacological study of the effects of some oral contraceptive drugs on certain aspects of carbohydrate metabolism in normal rats, M. T. Khayyal, M. E. El Sayed, H. M.S. Ahmed, and Mohamed M. Elmazar