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Submissions from 2023

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Fabrication and characterization of anti-rosacea 3D nanofibrous customized sheet masks as a novel scaffold for repurposed use of spironolactone with pre-clinical studies, Shady Swidan, Nahla A. Elhesaisy, Rasha A. Tawfiq, Mohamed El-Nabarawi, and Mahmoud Teaima

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Characterization, antibacterial, antioxidant, antidiabetic, and anti-inflammatory activities of green synthesized silver nanoparticles using Phragmanthera austroarabica A. G. Mill and J. A. Nyberg extract, Shady Swidan, Dina Khodeer, Sarah Shabayek, Ali Nasr, Roaa Khinkar, Mohammed Aldurdunji, Maryam Ramadan, and Jihan Badr

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Exploring the potential of intranasally administered naturally occurring quercetin loaded into polymeric nanocapsules as a novel platform for the treatment of anxiety, Shady Swidan, Khaled Younis Mahmoud, Nahla Ahmed Elhesaisy, Abdelrahman Rashed, Ebram Mikhael, Mahmoud Fadl, Mahmoud Elsadek, Merna Mohamed, Merna Mostafa, Mohamed Hassan, Omar Halema, and Youssef Elnemer

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Phytoecdysteroids and Anabolic Effect of Atriplex dimorphostegia: UPLC-PDA-MS/MS Profiling, In Silico and In Vivo Models, Noha Swilam, German University in Cairo (GUC), Singab, The British University in Egypt (BUE), and Iriny M. Ayoub

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Design of experiment-based green UPLC-DAD method for the simultaneous determination of indacaterol, glycopyrronium and mometasone in their combined dosage form and spiked human plasma, Mohamed Tarek, Nermine S. Ghoniem, Maha A. Hegazy, and Hebatallah Wagdy

Submissions from 2022

Antioxidant-biocompatible and stable catalase-based gelatin-alginate hydrogel scaffold with thermal wound healing capability: immobilization and delivery approach, Heidi Mohamed Abdel-Mageed, Amira Emad Abd El Aziz, Batoul Mohamed Abdel Raouf, Saleh Ahmed Mohamed, and Dina Nada

Optimization of catalytic properties of Mucor racemosus lipase through immobilization in a biocompatible alginate gelatin hydrogel matrix for free fatty acid production: a sustainable robust biocatalyst for ultrasound-assisted olive oil hydrolysis, Heidi Mohamed Abdel-Mageed, Dina Nada, Rasha Ali Radwan, Saleh Ahmed Mohamed, and Nesrine Abdelrehim E L Gohary

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2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights, Amgad Albohy

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2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights, Amgad Albohy

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Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (Mpro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis, Amgad Albohy

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Antiulcer Potential of Psidium guajava Seed Extract Supported by Metabolic Profiling and Molecular Docking, Amgad Albohy

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Biodiversity of N-acyl homoserine lactonase (aiiA) gene from Bacillus subtilis, Amgad Albohy

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Evaluation of antiviral activity of Carica papaya leaves against SARS-CoV-2 assisted by metabolomic profiling, Amgad Albohy

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Identifying the specific-targeted marine cerebrosides against SARS-CoV-2: An integrated computational approach, Amgad Albohy

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Metabolomic profiling of three Araucaria species, and their possible potential role against COVID-19, Amgad Albohy

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Multitarget in silico studies of Ocimum menthiifolium, family Lamiaceae against SARSCoV- 2 supported by molecular dynamics simulation, Amgad Albohy

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Neuroprotective repositioning and anti-tau effect of carvedilol on rotenone induced neurotoxicity in rats: Insights from an insilico& in vivo (InhA) inhibitors against Mycobacterium tuberculosis, Amgad Albohy

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Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights, Amgad Albohy

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Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades, Amgad Albohy

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Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity, Amgad Albohy

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Remdesivir analog as SARS-CoV-2 polymerase inhibitor: virtual screening of a database generated by scaffold replacement, Amgad Albohy, Mohamed A. Said, Mohamed A. Abdelrahman, and Hany Said

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Selective Engram Coreactivation In Idling Brain Inspires Implicit Learning, Mohamed H. Aly, Kareem Abdou, Reiko Okubo-Suzuki, Masanori Nomoto, and Kaoru Inokuchi

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Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome, Reham A. Ammar, Ahmed F. Mohamed, Mohamed M. Kamal, Marwa M. Safar, and Noha F. Abdelkader

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Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study, Dalia Attia, Caroline Lamie, Enas Elmowafy, Maha Ragaie, and Nahed Mortada

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Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors?, Dalia Attia; Caroline Lamie; Nahed Mortada; Mohey El-Mazar; and Enas Elmowafy,

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Screening of Adapalene Microsponges Fabrication Parameters with Insight on the In vitro Biological Effectiveness, Dalia Attia, Rania M Yehia, Mohey Elmazar, Mohamed A El-Nabarawi, and Mahmoud H Teaima

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Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma, Dalia Attia, Mahmoud Teaima, Noha Badawi, Mohamed El-Nabarawi, mohamed Elmazar, and Shaker Mousa

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Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery, Yasmeen M. Attia, Mustafa Maher, Olfat Hammam, Soheir Mahmoud, Wafaa Kandil, and Mohamed Salah

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Obeticholic acid orchestrates the crosstalk between ileal autophagy and tight junctions in non-alcoholic steatohepatitis: Role of TLR4/TGF-β1 axis, Yasmeen M. Attia, Rasha Tawfiq, Noha Nassar, Dalaal Abdallah, Olfat Hammam, Rasha Allam, and Mohamed Elmazar

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Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer, Noha Badawi, Yasmeen M. Attia, Dina M. El-Kersh, Olfat A. Hammam, and Maha KA Khalifa

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POST-TRAUMATIC STRESS DISORDER AND DIFFICULTIES IN EMOTION REGULATION AMONG UNIVERSITY STUDENTS UNDER THE COVID-19 CONDITION, Amani S. Elbarazi

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Supporting Women to Heal from Trauma and Post-Traumatic Stress Disorder, Amani S. Elbarazi and Salma Ahmed

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COGNITIVE PROCESSING THERAPY VERSUS MEDICATION FOR THE TREATMENT OF COMORBID SUBSTANCE USE DISORDER AND POST-TRAUMATIC STRESS DISORDER IN EGYPTIAN PATIENTS (RANDOMIZED CLINICAL TRIAL), Amani S. Elbarazi, Osama Badary, Mohey Elmazar, and Hanan Elrasas

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The Management of Social Anxiety: More Than 25 Years Later, Where are we?, Amani S. Elbarazi and Pierre Meshreky

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Cognitive Processing Therapy for the Treatment of PTSD, Depression and Anxiety in Syrian Refugees in Egypt, Amani S. Elbarazi, Rajiv Tikamdas, Salma Ahmed, and Salma Ramadan

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Characterization and anti-biofilm activity of bacteriophages against urinary tract Enterococcus faecalis isolates, Reham F. El-Kased, Doaa M. El-Atrees, Ahmad M. Abbas, and Mahmoud A. Yassien

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GC–MS Profiling of Naturally Extracted Essential Oils: Antimicrobial and Beverage Preservative Actions, Reham F. El-Kased and Dina M. El-Kersh

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Antioxidant, Antimicrobial Activities and Characterization of Polyphenol-Enriched Extract of Egyptian Celery (Apium graveolens L., Apiaceae) Aerial Parts via UPLC/ESI/TOF-MS, Reham F. El-Kased, Dalia M. Rasheed, Ayat M. Emad, and Dina M. El-Kersh

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Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking, Dina M. El-Kersh, Rania Abou El-Ezz, Marwa Fouad, and Mohamed Farag

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Natural acylated flavonoids: their chemistry and biological merits in context to molecular docking studies, Dina M. El-Kersh, Ahmed Essa, Mohamed Teleb, Abd El-Nasser G. El Gendy, Abdelsamed Elshamy, and Mohamed Farag

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Apple Pomace as a Source of Nutraceuticals, Dina M. El-Kersh, Shahira Ezzat, Maha M. Salama, and Mohamed Salem

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Unveiling major ethnopharmacological aspects of genus Diospyros in context to its chemical diversity: A comprehensive overview, Dina M. El-Kersh, Rola M. Labib, Fadia S. Youssef, and nada fareed

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GC-MS metabolites profiling of anethole-rich oils by different extraction techniques: antioxidant, cytotoxicity and in-silico enzymes inhibitory insights, Dina M. El-Kersh, Nada Mostafa, Shaimaa Fayez, Tarfah Al-Warhi, Mohammed Abourehab, Wagdy Eldehna, and Mohamed Salem

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GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study, Dina M. El-Kersh, Chandan Sarkar, Mondal Milon, Khattab Al-Khafaji, Sarmin Jamaddar, Pranta Ray, Uttam Kumar Roy, Mirola Afroze, Md. Moniruzzaman, Mala Khan, Umma Hafsa Asha, and Abul Bashar Ripon Khalipha

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Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats, Maham Eltimamy, Marwa Elshamarka, MArina Aboelsaad, Moustafa Sayed, and Helmy M. Sayed

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Diagnosis and staging of HCV associated fibrosis, cirrhosis and hepatocellular carcinoma with target identification for miR-650, 552-3p, 676-3p, 512-5p and 147b, Abdullah A.Y. Gibriel, M ISMAIL, H SLEEM, N ZAYED, A YOSRY, S EL-NAHAAS, and N SHEHATA

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Exendin‐4 enhances osteogenic differentiation of adipose tissue mesenchymal stem cells through the receptor activator of nuclear factor‐kappa B and osteoprotegerin signaling pathway, Sarah A. Habib, Mohamed M. Kamal, Shohda A. El-Maraghy, and Mahmoud A. Senousy

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The impact of the efflux transporter ABCG2 gene polymorphism on the development of adverse events in CML patients treated with Imatinib, MARWA HAMZA, SAMIA SHOUMAN, RAAFAT ABDELFATTAH, HEBA MOUSSA, and MERVAT OMRAN

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Determination of the Cut-off Value for Imatinib Plasma Levels Linked to Occurrence of Bone Pain in CML Patients, Marwa S. Hamza, Samia A. Shouman, Raafat Abdelfattah, Heba S. Moussa, and Mervat M. Omran

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Safety and Effectiveness of COVID-19 Vaccines: Results from a Cross-Sectional Survey among Staff, Workers and Students at an Egyptian University, Marwa S. Hamza, Rajiv Tikamdas, Noha S. Elbaghdady, Moustafa Sayed, Amani S. Elbarazi, Osama A. Badary, and mohamed M. Elmazar

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Comparative metabolite profiling of four polyphenol rich Morus leaves extracts in relation to their antibiofilm activity against Enterococcus faecalis, Yomna A. Hashem, Maha M. Salama, Shahira Ezzat, and Mohamed Salem

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Comparative metabolite profiling of four polyphenol rich Morus leaves extracts in relation to their antibiofilm activity against Enterococcus faecalis, Yomna Hashem, Maha M. Salama, Shahira Mohammed Ezzat, and Mohamed salem

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Antibiofilm activity of green synthesized silver nanoparticles against biofilm associated enterococcal urinary pathogens, Yomna Hashem, Nada Swidan, Walid F. Elkhatib, and Mahmoud A. Yassein

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Garcinia camobogia extract alters anxiety, sociability, and dopamine turnover in male Swiss albino mice, Michael Kamal Ibrahim, MArina Aboelsaad, Fatma Tony, and Moustafa Sayed

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Sources and Therapeutic Strategies of Mesenchymal Stem Cells in Regenerative Medicine, Mohamed M. Kamal and Dina H. Kassem

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Isolation of Rat Adipose Tissue Mesenchymal Stem Cells for Differentiation into Insulin-producing Cells, Dina H. Kassem, Sarah A. Habib, Omar I. Badr, and Mohamed M. Kamal

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Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances, Khaled Mahmoud, Shady Swidan, Mohamed A. El-Nabarawi, and Mahmoud H. Teaima

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The natural isoflavone Biochanin-A synergizes 5-fluorouracil anticancer activity in vitro and in vivo in Ehrlich solid-phase carcinoma model, Mohamed Mahmoud, Maha R.A. Abdollah, Mohamed E. Elsesy, Dalal A. Abou El Ella, Suher K. Zada, and Mai Fathy Tolba

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Assessment of the greenness of micellar HPLC method for rapid separation and simultaneous estimation of chlorpheniramine maleate in presence of some co-administered drugs in three pharmaceutical dosage forms using single run, Ekram Hany Mohamed

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Synthesis and characterization of new 1,3,4-thiadiazole derivatives: study of their antibacterial activity and CT-DNA binding, Ekram Hany Mohamed

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Smart nanovesicles for drug delivery, Ekram Hany Mohamed, Mohamed S. S. Attia, and M.S.A. Abdel-Mottaleb

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A highly selective and sensitive spectrofluorimetric method for the assessment of 3-nitrotyrosine in serum using (Eu(TTA)3Phen) photo probe, Ekram Hany Mohamed; Mohamed S. S. Attia; Ahmed O. Youssef; Nour El-Din A. Abdel-Sattar; Mohammed A. Amin,; Sarah Alharthi; Safwat A. Mahmoud,; and Mona N. Abou-Omar,

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Emerging advances and current applications of nanoMOF-based membranes for water treatment, Ekram Hany Mohamed; Mohamed S. S. Attia; Ahmed O. Youssef; Mona N. Abou-Omar,; Rabah Boukherroub; Altalhi Tariq; and Mohammed A. Amin

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Development of a multivariate model with desirability-based optimization for determination of atenolol and hydrochlorothiazide by eco-friendly HPLC method with fluorescence detection, Ekram Hany Mohamed; Ahmed Hemdan,; and Naser F. Al-Tannak,

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A novel cyanopyridine derived fluorescent sensor for selective determination of uranyl ions in different water samples, Ekram Hany Mohamed; Amany R Salem; Abeer M. El-Naggar,; Mohammed A. Amin,; and Mohamed S. S. Attia

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Kinetic Degradation Study of Ipragliflozin Coupled with MS/MS Structural Elucidation, Shereen Mowaka; Manar M. Elhassan,; Amr M. Mahmoud; and Maha A. Hegazy

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Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation, Shereen Mowaka, Haidy E. Michel, Mariam M. Tadros, Moataz S. Hendy, and Bassam M. Ayoub

Identification of FAT3 as a new candidate gene for adolescent idiopathic scoliosis, Dina Nada, cedric Julien, Simon Papillon-Cavanagh, Jacek Majewski, Mohamed Elbakry, Wesam Elremaly, Mark E Samuels, and Alain Moreau

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Cheminformatics Application in the Phytochemical and Biological Study of Eucalyptus globulus L. Bark as a Potential Hepatoprotective Drug, Khaled Nematallah, Sahar Elmekkawy, Maha Abdollah, mohamed Elmazar, Essam Abdel Sattar, and Meselhy R. Meselhy

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Enhanced Antioxidant, Antiviral, and Anticancer Activities of the Extract of Fermented Egyptian Rice Bran Complexed with Hydroxypropyl-β-cyclodextrin, Khaled Nematallah, Sherif Ashraf Fahmy, Noha Khalil Mahdy, Hesham El-Askry, Meselhy Ragab Meselhy, and Hassan El-Said Azzazy

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Modulation of Plasma 25-Hydroxyvitamin D3 Level by Imatinib Mesylate in Patients with Chronic Myelogenous Leukemia: The Role of Uptake and Efflux Transporters, Mervat Omran; Samia Shouman,; Raafat Abdelfattah; Heba Moussa; Nadia Thabet; and Marwa Hamza

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Phytochemical Constituents of Aquilaria malaccensis Leaf Extract and Their Anti-Inflammatory Activity against LPS/IFN-γ-Stimulated RAW 264.7 Cell Line, Eman Ramadan, Manar A. Eissa, Yumi Z. H-Y Hashim, and Dina M. EL-Kersh

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Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players, Nehal I. Rizk, Ahmed I. Abulsoud, Mohamed M. Kamal, Dina H. Kassem, and Nadia M. Hamdy

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Modulation of PTZ-induced convulsions in rats using topiramate alone or combined with low dose gamma irradiation: involving AKT/m-TOR pathway, Marwa Safar

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Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 infammasome, Marwa Safar

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Phosphodiesterase (PDE) III inhibitor, Cilostazol, improved memory impairment in aluminum chloride-treated rats: modulation of cAMP/CREB pathway, Marwa Safar

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Telmisartan: An Angiotensin Receptor Blocker Regulates Osteoclastogenesis via Inhibition of the ERK Triggering in Osteoporotic Male Rats, Marwa Safar

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Antibacterial and wound healing properties of cellulose acetate electrospun nanofibers loaded with bioactive glass nanoparticles; in-vivo study, S SHARAF, A EL-SHAFEI, R REFAIE, Abdullah Gibriel, and R ABDEL-SATTAR

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The impact of clinical pharmacist implemented education on the incidence of prescribing errors in COVID-19 patients, May A. Shawki, Nagwa A. Sabri, Ibrahim M. Dina, Mohamed M. Samady, and Marwa S. Hamza

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Comparative Cytotoxic Evaluation of Zygophyllum album Root and Aerial Parts of Different Extracts and Their Biosynthesized Silver Nanoparticles on Lung A549 and Prostate PC-3 Cancer Cell Lines, Shady Swidan

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Novel Repurposed Nano-Facial sheet masks For Dermatological Disease, Shady Swidan, Nahla Elheaisy, Mohamed Nabarawy, and Mahmoud Taeima

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Comparative Estimation of the Cytotoxic Activity of Different Parts of Cynara scolymus L.: Crude Extracts versus Green Synthesized Silver Nanoparticles with Apoptotic Investigation, Shady Swidan, Amgad Khedr, Abdelaziz Farrag, Ali Nasr, Mohamed Nafie, Maged Abdel-Kader, Marwa Goda, Jihan Badr, and Reda Abdelhameed

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Silver Nanoparticles Formulation of Flower Head’s Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation, Shady Swidan, Amgad Khedr, Marwa Goda, Abdelaziz Farrag, Ali Nasr, Mohamed Nafie, Maged Abdel-kader, Jihan Badr, and Reda Abdelhameed

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UPLC-PDA-MS/MS Profiling and Healing Activity of Polyphenol-Rich Fraction of Alhagi maurorum against Oral Ulcer in Rats, Noha Swilam, Hala El Zahar, Esther Menze, Heba Handousa, Mohamed El Shazly, and Nada Mostafa

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Karafsin, a Unique Mono-acylated Flavonoid Apiofurnoside from the Leaves of Apium graveolens var. secalinum Alef: In vitro and In vivo Anti-inflammatory Assessment, Noha Swilam, Mahmoud Nawwar, Eman Mostafa, Dalia Mostafa, and Mai Ragab

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Antidiabetic Activity and In Silico Molecular Docking of Polyphenols from Ammannia baccifera L. subsp. Aegyptiaca (Willd.) Koehne Waste: Structure Elucidation of Undescribed Acylated Flavonol Diglucoside, Noha Swilam, Mahmoud Nawwar, Rasha Radwan, and Eman Mostafa

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Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation, Sherouk M. Tawfik, Maha R.A. Abdollah, M. M. Elmazar, Hassan A. N. El-Fawal, and Anwar Abdelnaser

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Chapter 33 - Modeling neurotoxin-induced neuroinflammation with chemotherapy, Mai Fathy Tolba, Nada K. Sedky, Marwa A. Ali, and Maha R.A. Abdollah

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A short-term memory trace persists for days in the mouse hippocampus, Maha E. Wally, Masanori Nomoto, Kareem Abdou, Emi Murayama, and Kaoru Inokuchi

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Platelets' morphology, metabolic profile, exocytosis, and heterotypic aggregation with leukocytes in relation to severity and mortality of COVID-19-patients, Basma Yasseen, Aya Elkhodiry, Riem El-Messiery, Hajar El-sayed, Malak Elbenhawi, Azza Kamel, Shaimaa Gad, Mona Zidan, Marwa Hamza, Mohamed Al-ansary, Engy Abdel-Rahman, and Sameh Ali

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Cilostazol Alleviates NLRP3 Infammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories, Omnia S. Zaki, Noha N. Nassar, Dalaal M. Abdallah, Marwa Safar, and Reham A. Mohammed

Submissions from 2021

Rice Bran Extract Protected against LPS-Induced Neuroinflammation in Mice through Targeting PPAR-γ Nuclear Receptor, May A. Abd El Fattah, Yasmine A. Abdelhamid, Mohammed F. Elyamany, Osama A. Badary, and Ola A. Heikal

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Synthesis, molecular docking and biological evaluation of novel flavone derivatives as potential anticancer agents targeting akt, H Abo-salem, M El-Awady, A Mandour, and A Gibriel

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Application of nanoparticles in chiral analysis and chiral Separation, Hassan Y. Aboul-Enein, Nadia Bounoua, Mohamed Rebizi, and Hebatallah Wagdy

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Anti-inflammatory, antiallergic, and COVID-19 main protease (MPRO) inhibitory activities of butenolides from a marine-derived fungus aspergillus Terreus, Amgad Albohy

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Discovery of potent thieno[2,3-d]pyrimidine VEGFR-2 inhibitors: Design, synthesis and enzyme inhibitory evaluation supported by molecular dynamics simulations, Amgad Albohy

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Identifying the specific-targeted marine cerebrosides against SARS-CoV-2: An integrated computational approach, Amgad Albohy

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Isolation and Molecular Docking of Cytotoxic Secondary Metabolites from Two Red Sea Sponges of the Genus Diacarnus, Amgad Albohy

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Natural coumarins as potential anti-SARS-CoV-2 agents supported by docking analysis, Amgad Albohy

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Sansevieria: An Evaluation Of Potential Cytotoxic Activity In Reference To Metabolomic And Molecular Docking Studies, Amgad Albohy