Submissions from 2022
Antibacterial and wound healing properties of cellulose acetate electrospun nanofibers loaded with bioactive glass nanoparticles; in-vivo study, S SHARAF, A EL-SHAFEI, R REFAIE, Abdullah Gibriel, and R ABDEL-SATTAR
The impact of clinical pharmacist implemented education on the incidence of prescribing errors in COVID-19 patients, May A. Shawki, Nagwa A. Sabri, Ibrahim M. Dina, Mohamed M. Samady, and Marwa S. Hamza
Novel Repurposed Nano-Facial sheet masks For Dermatological Disease, Shady Swidan, Nahla Elheaisy, Mohamed Nabarawy, and Mahmoud Taeima
Comparative Estimation of the Cytotoxic Activity of Different Parts of Cynara scolymus L.: Crude Extracts versus Green Synthesized Silver Nanoparticles with Apoptotic Investigation, Shady Swidan, Amgad Khedr, Abdelaziz Farrag, Ali Nasr, Mohamed Nafie, Maged Abdel-Kader, Marwa Goda, Jihan Badr, and Reda Abdelhameed
Silver Nanoparticles Formulation of Flower Head’s Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation, Shady Swidan, Amgad Khedr, Marwa Goda, Abdelaziz Farrag, Ali Nasr, Mohamed Nafie, Maged Abdel-kader, Jihan Badr, and Reda Abdelhameed
UPLC-PDA-MS/MS Profiling and Healing Activity of Polyphenol-Rich Fraction of Alhagi maurorum against Oral Ulcer in Rats, Noha Swilam, Hala El Zahar, Esther Menze, Heba Handousa, Mohamed El Shazly, and Nada Mostafa
Karafsin, a Unique Mono-acylated Flavonoid Apiofurnoside from the Leaves of Apium graveolens var. secalinum Alef: In vitro and In vivo Anti-inflammatory Assessment, Noha Swilam, Mahmoud Nawwar, Eman Mostafa, Dalia Mostafa, and Mai Ragab
Antidiabetic Activity and In Silico Molecular Docking of Polyphenols from Ammannia baccifera L. subsp. Aegyptiaca (Willd.) Koehne Waste: Structure Elucidation of Undescribed Acylated Flavonol Diglucoside, Noha Swilam, Mahmoud Nawwar, Rasha Radwan, and Eman Mostafa
Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation, Sherouk M. Tawfik, Maha R.A. Abdollah, M. M. Elmazar, Hassan A. N. El-Fawal, and Anwar Abdelnaser
Chapter 33 - Modeling neurotoxin-induced neuroinflammation with chemotherapy, Mai Fathy Tolba, Nada K. Sedky, Marwa A. Ali, and Maha R.A. Abdollah
A short-term memory trace persists for days in the mouse hippocampus, Maha E. Wally, Masanori Nomoto, Kareem Abdou, Emi Murayama, and Kaoru Inokuchi
Platelets' morphology, metabolic profile, exocytosis, and heterotypic aggregation with leukocytes in relation to severity and mortality of COVID-19-patients, Basma Yasseen, Aya Elkhodiry, Riem El-Messiery, Hajar El-sayed, Malak Elbenhawi, Azza Kamel, Shaimaa Gad, Mona Zidan, Marwa Hamza, Mohamed Al-ansary, Engy Abdel-Rahman, and Sameh Ali
Cilostazol Alleviates NLRP3 Infammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories, Omnia S. Zaki, Noha N. Nassar, Dalaal M. Abdallah, Marwa Safar, and Reham A. Mohammed
Submissions from 2021
Rice Bran Extract Protected against LPS-Induced Neuroinflammation in Mice through Targeting PPAR-γ Nuclear Receptor, May A. Abd El Fattah, Yasmine A. Abdelhamid, Mohammed F. Elyamany, Osama A. Badary, and Ola A. Heikal
Synthesis, molecular docking and biological evaluation of novel flavone derivatives as potential anticancer agents targeting akt, H Abo-salem, M El-Awady, A Mandour, and A Gibriel
Application of nanoparticles in chiral analysis and chiral Separation, Hassan Y. Aboul-Enein, Nadia Bounoua, Mohamed Rebizi, and Hebatallah Wagdy
Identifying the specific-targeted marine cerebrosides against SARS-CoV-2: An integrated computational approach, Amgad Albohy
Isolation and Molecular Docking of Cytotoxic Secondary Metabolites from Two Red Sea Sponges of the Genus Diacarnus, Amgad Albohy
Natural coumarins as potential anti-SARS-CoV-2 agents supported by docking analysis, Amgad Albohy
Sansevieria: An Evaluation Of Potential Cytotoxic Activity In Reference To Metabolomic And Molecular Docking Studies, Amgad Albohy
Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis, Amgad Albohy
Neuroprotective repositioning and anti-tau effect of carvedilol on rotenone induced neurotoxicity in rats: Insig& in vivo anti-Parkinson’s disease studyhts from an insilico, Amgad Albohy, Rana kamal, Esther Menze, Hebatalla I. Ahmed, and Samar S. Azab
New Acaciin-Loaded Self-Assembled Nanofibers as MPro Inhibitors Against BCV as a Surrogate Model for SARS-CoV-2, Amgad Albohy, Soad A. Mohamad, Eman Maher Zahran, Maha Raafat Abdel Fadeel, and Mohamed A. Safwat
Importance of glutamine 189 flexibility in SARS-CoV-2 main protease: Lesson learned from in silico virtual screening of ChEMBL database and molecular dynamics, Amgad Albohy, Mohamed A. Said, Mohamed Abdelrahman, and Hany S. Ibrahim
Investigation of the relationship between CTLA4 and the tumor suppressor RASSF1A and the possible mediating role of STAT4 in a cohort of Egyptian patients infected with hepatitis C virus with and without hepatocellular carcinoma, N ALI, N HAMDY, A Gibriel, and H EL MESALLAMY
Downregulation of MMP1 expression mediates the anti-aging activity of Citrus sinensis peel extract nanoformulation in UV induced photoaging in mice, Dalia Attia, Reham Amer, Shahira Ezzat, Nora Aborehab, Mai Ragab, Dalia Mohamed, Amira Hashad, Maha Salama, and Mahitab El Bishbishy
Clinical comparative study of optimized metronidazole loaded lipid nanocarrier vaginal emulgel for management of bacterial vaginosis and its recurrence, Dalia Attia, Noha Badawi, Mona Elkafrawy, and Rania Yehia
In-vivo wound healing activity of a novel composite sponge loaded with mucilage and lipoidal matter of Hibiscus species, Dalia Attia, Riham Bakr, Reham Amer, Mai Abdelhafez, Asmaa Al-Mokaddem, Abd El-Nasser El-Gendy, Ahlam El-Fishawy, Marwa Fayed, and Sameh Gad
Augmented cytotoxicity using the physical adsorption of Poloxamer 188 on allicin-loaded gelatin nanoparticles, Dalia Attia, Muhammed Ossama, Rania Hathout, and Nahed Mortada
Activation of FXR modulates SOCS3/Jak2/STAT3 signaling axis in a NASH-dependent hepatocellular carcinoma animal model, Yasmeen M. Attia, Rasha Tawfiq, Aya Ali, Abdullah Gibriel, Dina Kassem, Olfat Hammam, and Mohamed Elmazar
Insights into the Impact of FXR Activation on Hepatic Autophagy in a Non-alcoholic Steatohepatitis Model., Yasmeen M. Attia, Rasha Tawfiq, Olfat Hammam, Noha Nassar, Dalaal Abdallah, and Mohamed Elmazar
Activation of FXR modulates SOCS3/Jak2/STAT3 signaling axis in a NASH-dependent hepatocellular carcinoma animal model, Y ATTIA, R TAWFIQ, Abdullah Gibriel, A ALI, D KASSEM, O HAMMAM, and M ELMAZAR
Economic Spectrofluorometric Bioanalysis of Empagliflozin in Rats’ Plasma, Bassam Ayoub, Noha M. Elzahar, Haidy Michel, and Mariam M. Tadros
Repurposing of Omarigliptin as a Neuroprotective Agent Based on Docking with A2A Adenosine and AChE Receptors, Brain GLP-1 Response and Its Brain/Plasma Concentration Ratio after 28 Days Multiple Doses in Rats Using LC-MS/MS, Bassam Ayoub, Haidy Michel, Shereen Mowaka, Moataz S. Hendy, and Mariam M. Tadros
HPLC/MSn Profiling and Healing Activity of a Muco-Adhesive Formula of Salvadora persica against Acetic Acid-Induced Oral Ulcer in Rats, Nahla Ayoub, Nadia Badr, Saeed S. Ai-Ghamdi, Safaa Alsanosi, Abdullah R. Alzahrani, Ashraf B. Abdel-Naim, Khaled Nematallah, and Noha Swilam
Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs, Osama A. Badary
Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure, Osama A. Badary, Marwa Samir Hamza, and Rajiv Tikamdas
Tailoring Terpesomes and Leciplex for the Effective Ocular Conveyance of Moxifloxacin Hydrochloride (Comparative Assessment): In-vitro, Ex-vivo, and In-vivo Evaluation, Noha Badawi, Rofida Albash, Menna Abdellatif, and Mariam Hassan
Nanographene Oxide for Enhanced Dissolution Rate and Antibacterial Activity of Cefdinir, Dina E. Bali, Mona F. Arafa, Noha M. Gamaleldin, and Gamal M. El Maghraby
SRD5A3-CDG: 3D structure modeling, clinical spectrum, and computer-based dysmorphic facial recognition, I Ben-Ayed, W Ouarda, F Frikha, F Kammoun, A Souissi, M Ben Said, A Bouzid, I Elloumi, T Hamdani, N Gharbi, N Baklouti, M Guirat, F Mejdoub, N Kharrat, I Boujelbene, F Abdelhedi, N Belguith, L Keskes, A GIBRIEL, H Kamoun, C Triki, A Alimi, and S MASMOUDI
Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation, Thomas J. Carter, Giulia Agliardi, Fang-Yu Lin, Matthew Ellis, Clare Jones, Mathew Robson, Angela Richard-Londt, Paul Southern, Mark Lythgoe, May Zaw Thin, Vyacheslav Ryzhov, Rafael T. M. de Rosales, Cordula Gruettner, Maha R.A. Abdollah, R. Barbara Pedley, Quentin A. Pankhurst, Tammy L. Kalber, Sebastian Brandner, Sergio Quezada, Paul Mulholland, Maxim Shevtsov, and Kerry Chester
Characterization of Four Piper Essential Oils (GC/MS and ATR-IR) Coupled to Chemometrics and Their anti- Helicobacter pylori Activity, Dina M. El-Kersh, Eman Al-Sayed, and Haidy Gad
A Literature-Based Update on Benincasa hispida (Thunb.) Cogn.: Traditional Uses, Nutraceutical, and Phytopharmacological Profiles, Dina M. El-Kersh; Muhammad Torequl Islam,; Cristina Quispe,; Manik Chandra Shill,; Kanchan Bhardwaj,; Prerna Bhardwaj,; Javad Sharifi-Rad,; Miquel Martorell,; Rajib Hossain,; Ahmed Al-Harrasi,; Ahmed Al-Rawahi,; and Monica Butnariu,
Monocyte monolayer assay in pre-transfusion testing: A magic key in transfusing patients with recurrent bad cross-match due to alloimmunization, Hebat Allah N. El-sayed, Maha R.A. Abdollah, Shereen N. Raafat, and Dina Ragab
Novel pathogenic mutations and further evidence for clinical relevance of genes and variants causing hearing impairment in Tunisian population, Abdullah A.Y. Gibriel, A Souissi, M BEN SAID, I Ben Ayed, I Elloumi, A Bouzid, M Mosrati, M Hasnaoui, M Belcadhi, N Idriss, H Kamoun, N Gharbi, Abdullah Gibriel, A Tlili, and S MASMOUDI
Glucose and fatty acid metabolism involved in the protective effect of metformin against ulipristal-induced endometrial changes in rats, Marwa S. Hamza, Eman Ramadan, and Salama A. Salama
Phenotype–Genotype Correlations and Distribution of Key Virulence Factors in Enterococcus faecalis Isolated from Patients with Urinary Tract Infections, Yomna Hashem, Ramy K. Aziz, and Khaled Abdelrahman
Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage, Amira Khalil, Mirat Sojitra, Jasmine Maghera, Emily Rodrigues, Eric J. Carpenter, Shaurya Seth, Daniel Ferrer Vinals, and Todd L. Lowary
Validation of a novel UPLC-MS/MS method for estimation of metformin and empagliflozin simultaneously in human plasma using freezing lipid precipitation approach and its application to pharmacokinetic study, Ekram Hany Mohamed; Mona N. Abou-Omar,; Mohamed S. S. Attia; Ahmed O. Youssef; Sarah Alharthi,; and M. Kenawy
Novel Optical Biosensor Based on a Nano-Gold Coated by Schiff Base Doped in Sol/Gel Matrix for Sensitive Screening of Oncomarker CA-125, Ekram Hany Mohamed; Mohamed S. S. Attia; Mona N. Abou-Omar,; Mohammed A. Amin,; Rabah Boukherroub; and hisham afify
Simultaneous determination of Avanafil and Dapoxetine in human plasma using liquid chromatography/tandem mass spectrometry (LC-MS/MS) based on a protein precipitation technique, Ekram Hany Mohamed; Mohamed S. S. Attia; Mona N. Abou-Omar,; Abdelaziz M Annadi,; Ahmed O. Youssef; Mohamed A. AMIN; and Noha M. El Zahar,
Tb3+-atorvastatin doped in poly(ethylene glycol) optical biosensor for selective determination of progesterone and testosterone in serum samples, Ekram Hany Mohamed; Mohamed S. S. Attia; Safwat A. Mahmoud,; Amal M. Ahmed,; Tarek A. Amin; Ahmed O. Youssef; Mona N. Abou-Omar,; and Mohammed A. c Amin,
New Tb3+-simvastatin optical biosensor for sensitive determination of folic acid, progesterone, testosterone and vitamin D3in biological fluids, Ekram Hany Mohamed; Mohamed S. S. Attia; Ahmed O. Youssef; Mona N. Abou-Omar,; Amal M. Ahmed,; Safwat A. Mahmoud,; Mohammed A. Amin; and tarek A. Mahmoud,
All solid-state miniaturized potentiometric sensors for flunitrazepam determination in beverages, Ekram Hany Mohamed, Mahmoud tantawy, and ali yahia
Deep analysis of the LRTOMTc.242G>A variant in non-syndromic hearing loss North African patients and the Berber population: Implications for genetic diagnosis and genealogical studies, M MOSRATI, K Fadhlaoui-Zid, A Benammar- Elgaaied, Abdullah Gibriel, M Ben Said, and S MASMOUDI
Investigation of Pharmacokinetic Parameters of Trelagliptin in Egyptian Volunteers Using Sensitive LC-MS/MS: A Comparative Study with a Japanese Population, Shereen Mowaka, Nermeen Ashoush, Mariam M. Tadros, and Bassam Ayoub
Fabrication and characterization of Agarwood extract-loaded nanocapsules and evaluation of their toxicity and anti-inflammatory activity on RAW 264.7 cells and in zebrafish embryos, Eman Ramadan, Manar A. Eissa, and Noha Badawi
Comparing the protective effects of resveratrol, curcumin and sulforaphane against LPS/IFN-γ-mediated inflammation in doxorubicin-treated macrophages, Eman Ramadan, Mohey Elmazar, and Haidy A. Saleh
'Induction of apoptosis, cytotoxicity and radiosensitization by novel 3,4-dihydroquinazolinone derivatives, Eman Ramadan and amira khalil
Novel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease, Eman Ramadan and marwa M. Safar
Novel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease., Marwa Safar
Rutin Ameliorates Hepatic Fibrosis via Targeting Hepatic Stellate Cells’ Activation, Proliferation and Apoptosis, Marwa Safar
Anti‑estrogenic and anti‑aromatase activities of citrus peels major compounds in breast cancer, Maha Salama, Dina Mahmoud ElKersh, Shahira M. Ezzat, Yasmeen Attiaa, Engy A. Mahrous, and Mohey ElMazar
Downregulation of MMP1 expression mediates the anti-aging activity of Citrus sinensis peel extract nanoformulation in UV induced photoaging in mice, Maha Salama, October University for Modern Sciences & Arts, and The British University in Egypt
Obesity and depression: Could some shared genes explain the relationship?, Moustafa Sayed and Nouran Yonis
Genetics and meta-analysis of recessive non-syndromic hearing impairment and Usher syndrome in Maghreb population: lessons from the past, contemporary actualities and future challenges, A Souissi, Abdullah Gibriel, and S MASMOUDI
Green Synthesized Honokiol Transfersomes Relieve the Immunosuppressive and Stem-Like Cell Characteristics of the Aggressive B16F10 Melanoma, Shady Swidan, Yasmeen Ezzeldeen, Aya Sebak, and Aliaa N. ElMeshad
Design, Synthesis, Anticancer Activity, and Solid Lipid Nanoparticle Formulation of Indole-and Benzimidazole-Based Compounds as Pro-Apoptotic Agents Targeting Bcl-2 Protein, Shady Swidan, Ali Nasr, Mona K. Qushawy, Manar Nagy, Khalid Darwish, Samia Mostafa, Ismail Salama, and Mohaamed Tantawy
GC/MSProfilingandExVivoAntibacterialActivityofSalvadora persica (Siwak) against Enterococcus faecalis as Intracanal Medicament, Noha Swilam; Nahla Ayoub; Nadia Badr; Saeed S Al-Ghamdi,; Arwa Alzahrani; Rahaf Alsulaimani; Afnan Nassar; and Rawabi Qadi
A Unique Acylated Flavonol Glycoside from Prunus persica (L.) var. Florida Prince: a New Solid Lipid Nanoparticle Cosmeceutical Formulation for Skincare, Noha Swilam, Eman Mostafa, Ahmed Maher, Dalia Mostafa, Sameh Gad, and Mahmoud Nawwar
Circulatory miR-221 & miR-542 expression profiles as potential molecular biomarkers in Hepatitis C Virus mediated liver cirrhosis and hepatocellular carcinoma, M YASSER, M AbdellatiF, E EMAD, A JAFER, S AHMED, L NAGEB, H Abdelshafy, A Al-anany, M Al-Arab, and A Gibriel
Impact of TNF-α Gene Polymorphisms on Pancreatic and Non-Small Cell Lung Cancer-Induced Cachexia in Adult Egyptian Patients: A Focus on Pathogenic Trajectories, Rana M. Yehia, Mona Schaalan, dalal abdallah, Amr Shafik, Nevine Sarhaan, and samira saleh
Submissions from 2020
Metallopharmaceutical complexes based on vanadium as potential anti-hyperglycemic agents, R. M. Abd-Elaziz, A. S. El-Tabl, Mohamed M. Elmazar, and M. M. Abd-Elwahed
Effects of TNF-α antagonist infliximab on fructose-induced metabolic syndrome in rats, Yasmine A. Abdelhamid, Mohammed F. Elyamany, Muhammad Y. Al-Shorbagy, and Osama A. Badary
Olmesartan attenuates type 2 diabetes-associated liver injury: Cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways, Nesma M.E. Abo El- Nasr, Dalia Osama Saleh, Sawsan S. Mahmoud, Salwa M. Nofal, Rania M. Abdelsalam, Marwa M. Safar, and Hanan S. El-Abhar
Development and validation of HPLC-UV method for the determination of a potent synthetic cannabinoid THJ-2201 in mouse plasma and application in a pharmacokinetic study, Hassan Y. Aboul-Enein, Gamal A.E. Mostafa, Haitham Alrabiah, Mohammed Al-Ramadi, Sabry M. Attia, and Hebatallah Wagdy
Investigating circulatory microRNA expression profiles in Egyptian patients infected with hepatitis C virus mediated hepatic disorders, Amany Al-Anany, Mohamed Al-Arab, Hassan Azzazy, and Abdullah Gibriel
Synthesis and Docking Studies of a Novel Tetrahydroquinazoline Derivative as Promising Scaffold for Acetylcholine Esterase Inhibition, Amgad Albohy; Rawan A. , Alsuhaimat; Qais Abualassal; Zead Helmi Abudayeh; and Sherif S. Ebada
Publisher Correction: Propolis-based niosomes as oromuco-adhesive films: A randomized clinical trial of a therapeutic drug delivery platform for the treatment of oral recurrent aphthous ulcers (Scientific Reports, (2018), 8, 1, (18056), 10.1038/s41598-018-37157-7), Mona G. Arafa, Dalia Ghalwash, Dina M. El-Kersh, and Mohamed M. Elmazar
Chitosan-coated PLGA nanoparticles for enhanced ocular anti-inflammatory efficacy of atorvastatin calcium, Mona Arafa, Germeen N.S. Girgis, and Marwa S. El-Dahan
Preparation of PLGA-chitosan based nanocarriers for enhancing antibacterial effect of ciprofloxacin in root canal infection, Mona Arafa, Hadeel A. Mousa, and Nagia N. Afifi
Development of Pomegranate Extract-Loaded Solid Lipid Nanoparticles: Quality by Design Approach to Screen the Variables Affecting the Quality Attributes and Characterization, Dalia Attia, Noha Badawi, Khalid El-Say, Mohamed El-Nabarawi, mohamed Elmazar, and Mahmoud Teaima
Management of recurrent aphthous ulcers exploiting polymer-based Muco-adhesive sponges: in-vitro and in-vivo evaluation, Dalia Attia, Muhammed Ossama, Caroline Lamie, Mohamed Tarek, Hebatallah Wagdy, and mohamed Elmazar
Inhibition of aldehyde dehydrogenase-1 and p-glycoprotein-mediated multidrug resistance by curcumin and vitamin D3 increases sensitivity to paclitaxel in breast cancer, Yasmeen M. Attia, Dina M. El-Kersh, Reham A. Ammar, Aliaa Adel, Aya Khalil, Hoda Walid, Kirullos Eskander, Mohamed Hamdy, Nada Reda, Nour Elhoda Mohsen, Ghada M. Al-Toukhy, Mohamed Tarek Mansour, and Mohamed M. Elmazar