Submissions from 2025
Unlocking the therapeutic potential of canagliflozin in NAFLD: Insights into AMPK/SIRT1-mediated lipophagy, Nahla Elashmawy, Ghada M. Al-Ashmawy, Asmaa A. Kamel, and Eman G. Khedr
Cuproptosis Regulation by Long Noncoding RNAs: Mechanistic Insights and Clinical Implications in Cancer, Nahla Elashmawy, Eman G. Khedr, Mariam A. Abo-Saif, and Sarah M. Hamouda
Competing Endogenous RNAs Network and Therapeutic Implications: New Horizons in Disease Research., Nahla Elashmawy, Eman G. Khedr, Renad T. Darwish, and Amira O. Ibrahim
Flexible Nonenzymatic Glucose Biosensor Based on Magnetoelectrochemical Deposition of Cu, Desmond S. Iddirisu, Manar M. Elhassan, Dalton L. Glasco, William T. McLeod, Pedaballi Sireesha, Sarah Farahani, and Jeffrey G. Bell
The interplay of knowledge, motivation, and treatment response in medication adherence among patients with chronic myeloid leukemia treated with Imatinib, Mervat M Omran, Amel B Ibrahim, Raafat Abdelfattah, Heba S Moussa, Samia A Shouman, and Marwa Hamza
Gastroprotective Effect of Linagliptin on Indomethacin-Induced Gastric Ulceration in Mice: Crosstalk Between Oxidative Stress and Inflammasome Pathways, Maha E. Wally and Mohamed H. Aly
The role of neutrophilia in hyperlactatemia, blood acidosis, impaired oxygen transport, and mortality outcome in critically ill COVID-19 patients, Basma A Yasseen, Aya A Elkhodiry, Hajar El-Sayed, Mona Zidan, Azza G Kamel, Mohamed A Badawy, Marwa Hamza, Riem M El-Messiery, Mohamed El Ansary, Engy A Abdel-Rahman, and Sameh S Ali
Submissions from 2024
Integration of Pan-Cancer Cell Line and Single-Cell Transcriptomic Profiles Enables Inference of Therapeutic Vulnerabilities in Heterogeneous Tumors, Israa Abdelbar, Danielle Maeser, Weijie Zhang, Adam Lee, Yingbo Huang, Robert Gruener, Sampreeti Jena, Anand Patel, and R. Stephanie Huang
Prefrontal coding of learned and inferred knowledge during REM and NREM sleep, Kareem Abdou, Masanori Nomoto, Mohamed H. Aly, Ahmed Z. Ibrahim, Kiriko Choko, Reiko Okubo-Suzuki, Shin-ichi Muramatsu, and Kaoru Inokuchi
Eco-Friendly Synchronous Spectrofluorimetric Method for Simultaneous Determination of Remdesivir and Acetyl Salicylic Acid in Spiked Human Plasma, Sohair M. aboelghar, Maha A. Hegazy, and Hebatallah Wagdy
Ecofriendly bioanalytical validated RP-HPLC method for simultaneous determination of COVID-19 co-prescribed drugs employing quality by design and green chemistry, Sohair M. Aboelghar, Maha A. Hegazy, and Hebatallah A. Wagdy
Drug repurposing of pyrazolotriazine derivatives as potential anti‑SARS‑CoV‑2 agents: in vitro and in silico studies, Amgad Albohy and Khaled abouzid
In silico identifcation of new potential inhibitors of quorum sensing by Gram‑positive bacteria through specialized molecular docking, Amgad Albohy, Najla A. Obaid, Mariam Mojally, Mohammed Abou Rehab, and Najd Ahmad Alkhudhir
In silico identification of new potential inhibitors of quorum sensing by Gram‑positive bacteria through specialized molecular docking, Amgad Albohy, Najla A. Obaid, Mariam Mojally, and Najd Ahmad Alkhudhir
Drug repurposing of pyrazolotriazine derivatives as potential anti‑SARS‑CoV‑2 agents: in vitro and in silico studies, Amgad Albohy, Khulood H. Oudah, Mazin A. A. Najm, Reham F. Barghash, Omnia Kutkat, Mohamed GabAllah, and Khaled A. M. Abouzid
Epigallocatechin-3-gallate loaded proliposomal vesicles for management of traumatic brain injury: In-vitro and in-vivo evaluation, Aya Al-Najjar, Maha Khalifa, Omnya Amin, and Noha Badawy
Epigallocatechin-3-gallate loaded proliposomal vesicles for management of traumatic brain injury: In-vitro and in-vivo evaluation, Aya Al-Najjar, Maha Khalifa, Omnya Amin, and Noha Badawy
Protective effect of astaxanthin on indomethacin-induced gastric ulcerations in mice, Mohamed H. Aly, Aya K. Said, Aya M. Farghaly, Dalia A. Eldaly, Dina S. Ahmed, Maram H. Gomaa, Nazih H. Elgebaly, Omar Sameh, Salma K. Elahwany, Tasneem T. Ebrahem, Youssif Sameh, and Maha E. Wally
Harnessing adrenergic blockade in stress-promoted TNBC in vitro and solid tumor in vivo: disrupting HIF-1α and GSK-3β/β-catenin driven resistance to doxorubicin, Yasmeen M. Attia, Andrew Hakeem, Rawda Samir, Aya Mohammed, Abdullrahman Elsayed, Alaa Khallaf, Eman Essam, Hossameldeen Amin, Sarah Abdullah, Salwan Hikmat, Tarek Hossam, Ziad Mohamed, Ziad Aboelmagd, and Olfat Hammam
Chewing gum containing repaglinide solid dispersion using mesoporous silica nanoparticles for management of diabetes mellitus: In-vitro evaluation and clinical appraisal, Noha Badawy, Dalia Attia, Reham Amer, Ahmed Fayez, and Marwa Dawoud
Formulation and optimization of surfactant-modified chitosan nanoparticles loaded with cefdinir for novel topical drug delivery: Elevating wound healing efficacy with enhanced antibacterial properties, Merna Badie, Mahmoud Teaima, Mohamed El-Nabarawi, and Noha Badawy
Unlocking the potential of chitosan-based polymeric nanoparticles for the treatment of neurological disorders, Manar Eissa, Yumi Hashim, and Noha Badawy
The role of ABCG2 in health and disease: Linking cancer therapy resistance and other disorders, Nahla Elashmawy, Ghada Mohamed Al-Ashmawy, Omnia Basiony Hamada, and Naglaa Fathy Khedr
Prostate cancer and the cell cycle: Focusing on the role of microRNAs, Nahla Elashmawy, Ibrahim M. Elazab, Ola A. El-Feky, and Eman G. Khedr
Emerging role of natural lipophagy modulators in metabolic dysfunction-associated steatotic liver disease, Nahla Elashmawy, Eman G. Khedr, Ghada M. Al-Ashmawy, and Asmaa A. Kame
Suppression of inflammation in ulcerative colitis rats by avocado and pomegranate, Nahla Elashmawy, Eman G. Khedr, Enas A. El-Zamarany, and Sarah M. Ahmed
Adherence to Oral Hormonal Treatment among Breast Cancer Patients in Egypt, Noha S. El Baghdady, May Mohamed El Gazzar, Abdelrahman Magdy Abdo, Ahmed Mohamed Magdy, Farah Abdelghaffar Youssef, Kareem Amr Sayed, Mohamed Mahmoud Hussien, Joseph Essam Megala, Salma Hossam Eldien, Zeyad Mohsen Elmaboud, Hesham Mohamed Mostafa, and Nada Hazem Farrag
Potentiometric detection of apomorphine in human plasma using a 3D printed sensor, Manar Elhassan, Dalton Glasco, Anjaiah Sheelam, amr mahmoud, Maha Hegazy, Shereen Mowaka, and Jeffrey Bell
Potentiometric Detection of Apomorphine in Human Plasma Using a 3D Printed Sensor, Manar M. Elhassan, Dalton L. Glasco, Anjaiah Sheelam, Amr M. Mahmoud, Maha A. Hegazy, Shereen Mowaka, and Jeffrey G. Bell
Unlocking milk thistle's anti-psoriatic potential in mice: Targeting PI3K/AKT/mTOR and KEAP1/NRF2/NF-κB pathways to modulate inflammation and oxidative stress, Dina M. El-Kersh
Metabolic profiling of Vitex Pubescens Vahl bark via UPLC-ESI-QTOF/MS/MS analysis and evaluation of its antioxidant and acetylcholinesterase inhibitory activities, Dina M. El-Kersh and safa Abdel Baset
In vitro and in vivo burn healing study of standardized propolis: unveiling its antibacterial, antioxidant and anti-inflammatory actions in relation to its phytochemical profiling, Dina M. El-Kersh, Rania F. Abou El-Ezz, Eman Ramadan, and Reham F. El-Kased
Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells, Dina M. El-Kersh and Yasmeen attia
In vitro and in vivo burn healing study of standardized propolis: Unveiling its antibacterial, antioxidant and antiinflammatory actions in relation to its phytochemical profiling, Dina M. El-Kersh, Reham El-Kased, and Eman Ramadan
Nanofiberous facemasks as protectives against pandemic respiratory viruses, Merna H. Emam, Reham S. Elazab, Shady Swidan, and Rania M. Hathout
Integration of 3D Printed Mg2+ Potentiometric Sensors into Microfluidic Devices for Bioanalysis, Sarah Farahani, Dalton L. Glasco, Manar M. Elhassan, Pedaballi Sireesha, and Jeffrey G. Bell
PREPARATION, CHARACTERIZATION AND BIOMEDICAL APPLICATIONS OF ELECTROSPUN CELLULOSE ACETATE NANOFIBER DRESSING FABRICATED WITH SILVER AND BIOGLASS NANOPARTICLES FOR EFFICIENT WOUND HEALING IN STREPTOZOTOCIN INDUCED DIABETIC RAT, Abdullah A.Y. Gibriel, Raghda Abdel-Sattar, and Samar Sharaf
Nonenzymatic Detection of Glucose Using 3D Printed Carbon Electrodes in Human Saliva, Dalton L. Glasco, Manar M. Elhassan, William T. McLeod, and Jeffrey G. Bell
Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells, Andrew Hakeem, Dina El-kersh, Olfat Hammam, Aliaa Elhosseiny, Amr Zaki, Kohinour Kamel, Lidia Yasser, Marina Barsom, Menatallah Ahmed, Mohamed Gamal, and Yasmeen M. Attia
Genotype–phenotype correlation of fecal Streptococcus regulator (fsr) locus with gelatinase activity and bioflm formation intensity in clinical E. faecalis isolates, Yomna Hashem, Ramy K. Aziz, Khaled Abdelnasser Abdelrahman, and Mona Tawfik Kashef
Rosemary and neem: an insight into their combined anti-dandruff and anti-hair loss efficacy, Yomna Hashem, Mona M. Hashem, Maha M. Salama, Dalia A. Attia, Moataz Sobhy, Safa Abdelbaset, and Farah Adel
ISOLATION AND IDENTIFICATION OF NOVEL BACTERIAL STRAINS WITH CRYSTAL VIOLET BIODEGRADATION POTENTIAL FROM TEXTILE EFFLUENT WASTEWATER IN EGYPT, Yomna Hashem and Dina Osama
Therapeutic drug monitoring of six contraindicated/co-administered drugs by simple and green RP-HPLC-PDA; application to spiked human plasma, Nada Hesham, Maha A. Hegazy, and Hebatallah A. Wagdy
Electrochemical Sensor for Therapeutic Monitoring of Ganciclovir in Spiked Plasma Samples Using a Carbon Paste Electrode Modified with CuO nanoparticles, Nada Hesham, Amr M. Mahmoud, Maha A. Hegazy, and Hebatallah A. Wagdy
Electrochemical Sensor Modified with Graphene Oxide Decorated with Copper Oxide Nanoparticles for Velpatasvir’s Monitoring in Spiked Human Plasma, Nada Hesham, Amr M. Mahmoud, Maha A. Hegazy, and Hebatallah A. Wagdy
Cutting-edge biomaterials for advanced biomedical uses: self-gelation of l-arginine-loaded chitosan/PVA/vanillin hydrogel for accelerating topical wound healing and skin regeneration, Rabab Ibrahim, Elbadawy Kamoun, Noha Badawy, Shahira EL-Moslamy, Mahmoud Kh., and samar A. salim
Intranasal delivery of chitosan-based nanoparticles as an innovative way for management of neurodegenerative disorders: A comprehensive review of advanced strategies for CNS targeting, Rabab M. Ibrahim, Mahmoud Teaima, Mohamed El-Nabarawi, and Noha Badawy
Silencing of forkhead box protein O-1 (FOXO-1) enhances insulin-producing cell generation from adipose mesenchymal stem cells for diabetes therapy, Mohamed M. Kamal, Reham A. Ammar, and Dina H. Kassem
Adipose-Derived Mesenchymal Stem Cells and Their Derived Epidermal Progenitor Cells Conditioned Media Ameliorate Skin Aging in Rats, Mohamed M. Kamal, Omar Ibrahim Badr, and Tasnim Mahmoud
The effect of diabetes mellitus on differentiation of mesenchymal stem cells into insulin-producing cells, Mohamed M. Kamal, Omar I. Badr, Shohda A. El-Maraghy, and Heba R. Ghaiad
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review, Maha Khalifa, Somaia Abdel-Sattar, Omnya Amin, Neveen Kohaf, Heba Zaky, Marwa Abd El‑Fattah, Kamilia Mohammed, Noha Badawy, Ihab Mansoor, and Heba Eassa
Voltammetric analysis of pholcodine on graphene-modified GNPs/PTs with green assessment, Ekram Hany Mohamed, nahla abdel shafy, hadeer elkhouly, nehal khoudary, hany darwish, aswak alanzi, and ibrahim naguib
Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine, Ekram Hany Mohamed, hany batakoushy, adel ibrahim, zeinab adel, marwa soliman, sona abarghahash, tahanay mohamed, and fatma fouad
Smart sequential spectrophotometric analysis of Fluconazole and its two toxic official impurities having superimposed spectra; Greenness, whiteness, blueness assessment and in silico toxicity profiling, Ekram Hany Mohamed, christine magued elmaraghy, and mai saeed
Two green UV-spectrophotometric techniques applying successive and progressive resolution with new concepts for simultaneous determination of completely overlapping ternary mixture, Ekram Hany Mohamed, Menna hesham, ehab elkady, and sally mohkles
Polymer-Based Terbium Complex as a Fluorescent Probe for Cancer Antigen 125 Detection: A Promising Tool for Early Diagnosis of Ovarian Cancer, Ekram Hany Mohamed, magda mohamed, esraa el shahat, mohamed attia, hisham gamal, and akram eldidamony
MicroRNA-205-5p inhibits the growth and migration of breast cancer through targeting Wnt/β-catenin co-receptor LRP6 and interacting with lncRNAs, Sameh Hossam Mohamed, Mohamed M. Kamal, Ahmed Reda, Noha Mesbah, Dina Abo-Almatty, and Asmaa Abdel-Hamed
From beverage to anticancer agent: The repurposing of green coffee bean extract loaded in solid lipid nanoparticles, Yomna Moussa, Mahmoud H. Teaima, mohamed Elmazar, Dalia Attia, and Mohamed A. El-Nabarawi
Design, synthesis, and anti-MCF-7 activity of new Thieno[2,3-d]Pyrimidinone derivatives as potential breast cancer treatment, Bassem H. Naguib, Amgad Albohy, Mostafa A. Abdelaziz, and Hanan H. Kadry
Phytotherapeutic approach to enhance the hepatoprotective activity of some edible plants: Molecular docking and nanoformulation, Khaled Nematallah, Amgad Abdallah, and Noha Swilam
Phytotherapeutic approach to enhance the hepatoprotective activity of some edible plants: Molecular docking and nanoformulation, Khaled Nematallah, Amgad Albohy, and Noha Swilam
Phytotherapeutic approach to enhance the hepatoprotective activity of some edible plants: Molecular docking and nanoformulation, Khaled Nematallah, Amgad Albohy, and Noha Swilam
Imatinib pharmacokinetics and creatine kinase levels in chronic myeloid leukemia patients: implications for therapeutic response and monitoring, Mervat A. Omran, Amel B. Ibrahim, Raafat Abdelfattah, Samia A. Shouman, and Marwa Hamza
Revealing the role of serum exosomal novel long non-coding RNA NAMPT-AS as a promising diagnostic/prognostic biomarker in colorectal cancer patients, Nehal I. Rizk, Dina Kassem, Ahmed I. Abulsoud, Sherif Abdelhalim, Montasser Bellah Yasser, Mohamed M. Kamal, and Nadia M. Hamdy
Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors, Marwa M. Safar Prof. Dr.
Novel 3,6-disubstituted pyridazine derivatives targeting JNK1 pathway: Scaffold hopping and hybridization-based design, synthesis, molecular modeling, in vitro and in vivo anticancer evaluation., Mai M. Shaalan, Essam Eldin A. Osman, Yasmeen M. Attia, Olfat A. Hammam, Riham F. George, and Bassem H. Naguib
Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice, Shady Swidan, Hesham Hafez, Rehab Hosni, and Hatem Amin
Pharmacokinetics of pulmonary indacaterol in rat lung using molecular imprinting solid-phase extraction coupled with RP-UPLC, Mohamed Tarek, Nermine S. Ghoneim, Maha A. Hegazy, and Hebatallah Wagdy
Stability‐indicating UPLC assay coupled with mass spectrometry for the analysis of vilanterol degradation products in human urine, Mohamed Tarek, Hebatallah A. Wagdy, Maha A. Hegazy, and Nermine S. Ghoniem
Resolving acne with optimized adapalene microspongeal gel, in vivo and clinical evaluations, Rania Yehia, Dalia Attia, and M. M. Elmazar
Microsponges-Mediated Targeted Topical Delivery of Rosemary Oil for Hair Growth Promotion: Optimization and In-Vivo Studies, Rania Yehia, Caroline Lamie, and Dalia A. Attia
Submissions from 2023
Insights into the role of vitamin D in targeting the culprits of non-alcoholic fatty liver disease, Basma Abdelrahman, Aiman El-Khatib, and Yasmeen M. Attia
The role of vitamin D3 in modulating the interplay between NLRP3 inflammasome and autophagy in NASH, Basma Abdelrahman, Olfat Hammam, Aiman El-Khatib, and Yasmeen M. Attia
Antiangiogenic drugs in combination with seaweed fucoidan: A mechanistic in vitro and in vivo study exploring the VEGF receptor and its downstream signaling molecules in hepatic cancer, Maha R.A. Abdollah, Aya A. Ali, Hassnaa Hamed Elgohary, and M. M. Elmazar
Africa Guidelines for Hepatocellular Carcinoma Buildup Process, Ghassan Abou-Alfa, Mary Afihene, Marinela Capanu, Joanne Chou, Akwi Asombang, Olusegun Alatise, Adda Bounedjar, Lina Cunha, Hailemichael Mekonnen, Papa Diop, Reda Elwakil, Mahamat Ali, Ntokozo Ndlovu, Jerry Ndumbalo, Precious Makondi, Christian Tzeuton, Tiago Castria, Adwoa Afrakoma Agyei-Nkansah, Fiyinfolu Balogun, Alain Bougouma, Blaise Ibara, Eduard Jonas, Stephen Kimani, Peter Kingham, Reshad Kurrimbukus, Nazik Hammad, Mona Fouad, Noha S. El Baghdady, Eloumou Fiacre, Vikash Sewram, C. Wendy Spearman, Ju Yang, Lewis Roberts, and Ashraf Abdelaziz
https://www.sciencedirect.com/science/article/abs/pii/S0378874123004993?via%3Dihub, Amgad Albohy
Investigations on the cytotoxicity and antimicrobial activities of terezine E and 14-hydroxyterezine D, Amgad Albohy
Marine-Based Candidates as Potential RSK1 Inhibitors: A Computational Study, Amgad Albohy, Mousa AlTarabeen, Peter Proksch, Qosay Al-Balas, and Werner Ernst Georg Müller
Functionalized surface of PLGA nanoparticles in thermosensitive gel to enhance the efficacy of antibiotics against antibiotic resistant infections in endodontics: A randomized clinical trial, Mona Arafa, Hadeel Moussa, and Mohamed Medhat Kataia
Adrenergic Blockade in Stress-Promoted Breast Cancer: Impact on Doxorubicin Chemoresistance, Yasmeen M. Attia
Vitamin D3 and NLRP3 inflammasome modulation in non-alcoholic steatohepatitis: Is it autophagy-dependent or -independent?, Yasmeen M. Attia and Basma Abdelrahman
Effect of vitamin D receptor signaling on endoplasmic reticulum stress in non-alcohol related steatohepatitis: exploring potential autophagy dependence., Yasmeen M. Attia, Basma Abdelrahman, Aiman El-Khatib, and Olfat Hammam
Vitamin D3: Clueing into the crosstalk between HIF1α and macrophage polarization in NASH, Yasmeen M. Attia, Basma Abdelrahman, Olfat Hammam, and Aiman El-Khatib
FXR activation in breast cancer: Friend or foe?, Yasmeen M. Attia, Aya Ali, Olfat Hammam, and May Galal
Simvastatin suppresses the in vitro proliferation of cholesterol-enriched MCF-7 cells along with tumor growth in an in vivo model of breast cancer., Yasmeen M. Attia, Yasmine Amin, Mahmoud Khattab, and Olfat Hammam
Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes, Yasmeen M. Attia, Andrew Hakeem, Basma Abdelrahman, Rasha Tawfiq, Mohamed Kamal, Olfat Hammam, Mohamed Elmazar, and Aiman El-Khatib
Unravelling an autophagy-dependent role of vitamin D in preserving gut integrity in experimental NASH, Yasmeen M. Attia, Andrew Hakeem, Olfat Hammam, Aiman El-Khatib, Mahmoud Khattab, and Basma Abdelrahman
Combining non-selective beta-blockers with sorafenib in HCC: targeting the culprits of metastasis, Yasmeen M. Attia, Tasnim Mahmoud, Olfat Hammam, Aiman El-Khatib, and Mahmoud Khattab
Gut-liver crosstalk in hepatocellular carcinoma and non-selective beta-blockers: is there a link?, Yasmeen M. Attia, Tasnim Mahmoud, Olfat Hammam, Aiman El-Khatib, and Mahmoud Khattab
Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation, Noha Badawi, Rania Yehia, Caroline Lamie, Khaled Abdelrahman, Dalia Attia, and Doaa Helal
Simple green RP-UPLC method for the analysis of ganciclovir in its bulk form and pharmaceutical preparations, Semirna Daniel, Fatma Gamal, Nada Saad, Hala Hamdy, Ghada Adel, Mahmoud Elnahas, Fady Wael, Sohair Aboelghar, Nada Hesham, Mohamed Tarek, and Hebatallah A. Wagdy
Association Between COVID-19 Vaccination and Quality of Life Among University Students, Amani S. Elbarazi
Childhood Maltreatment and its Mental Health Consequences among University's Students, Amani S. Elbarazi
How Social Media Affects People’s Ideas on Sexist Behaviours and Gender-Based Violence, Amani S. Elbarazi
Psychological Support for Earthquake Survivors in Turkey and Syria, Amani S. Elbarazi