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Submissions from 2023

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Antiangiogenic drugs in combination with seaweed fucoidan: A mechanistic in vitro and in vivo study exploring the VEGF receptor and its downstream signaling molecules in hepatic cancer, Maha R.A. Abdollah, Aya A. Ali, Hassnaa Hamed Elgohary, and M. M. Elmazar

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https://www.sciencedirect.com/science/article/abs/pii/S0378874123004993?via%3Dihub, Amgad Albohy

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Impact of Eucalyptus maculata Hook resin exudate constituents on reducing COX-2 gene expression: In-vivo anti-inflammatory, molecular docking and dynamics studies, Amgad Albohy

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Investigations on the cytotoxicity and antimicrobial activities of terezine E and 14-hydroxyterezine D, Amgad Albohy

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Functionalized surface of PLGA nanoparticles in thermosensitive gel to enhance the efficacy of antibiotics against antibiotic resistant infections in endodontics: A randomized clinical trial, Mona Arafa, Hadeel Moussa, and Mohamed Medhat Kataia

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Adrenergic Blockade in Stress-Promoted Breast Cancer: Impact on Doxorubicin Chemoresistance, Yasmeen M. Attia

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Size-optimized simvastatin-loaded TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: Role of PTEN/AKT signaling, Yasmeen M. Attia

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Vitamin D3 and NLRP3 inflammasome modulation in non-alcoholic steatohepatitis: Is it autophagy-dependent or -independent?, Yasmeen M. Attia and Basma Abdelrahman

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Effect of vitamin D receptor signaling on endoplasmic reticulum stress in non-alcohol related steatohepatitis: exploring potential autophagy dependence., Yasmeen M. Attia, Basma Abdelrahman, Aiman El-Khatib, and Olfat Hammam

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Vitamin D3: Clueing into the crosstalk between HIF1α and macrophage polarization in NASH, Yasmeen M. Attia, Basma Abdelrahman, Olfat Hammam, and Aiman El-Khatib

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FXR activation in breast cancer: Friend or foe?, Yasmeen M. Attia, Aya Ali, Olfat Hammam, and May Galal

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Simvastatin suppresses the in vitro proliferation of cholesterol-enriched MCF-7 cells along with tumor growth in an in vivo model of breast cancer., Yasmeen M. Attia, Yasmine Amin, Mahmoud Khattab, and Olfat Hammam

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Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes, Yasmeen M. Attia, Andrew Hakeem, Basma Abdelrahman, Rasha Tawfiq, Mohamed Kamal, Olfat Hammam, Mohamed Elmazar, and Aiman El-Khatib

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Unravelling an autophagy-dependent role of vitamin D in preserving gut integrity in experimental NASH, Yasmeen M. Attia, Andrew Hakeem, Olfat Hammam, Aiman El-Khatib, Mahmoud Khattab, and Basma Abdelrahman

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Combining non-selective beta-blockers with sorafenib in HCC: targeting the culprits of metastasis, Yasmeen M. Attia, Tasnim Mahmoud, Olfat Hammam, Aiman El-Khatib, and Mahmoud Khattab

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Gut-liver crosstalk in hepatocellular carcinoma and non-selective beta-blockers: is there a link?, Yasmeen M. Attia, Tasnim Mahmoud, Olfat Hammam, Aiman El-Khatib, and Mahmoud Khattab

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Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation, Noha Badawi, Rania Yehia, Caroline Lamie, Khaled Abdelrahman, Dalia Attia, and Doaa Helal

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Simple green RP-UPLC method for the analysis of ganciclovir in its bulk form and pharmaceutical preparations, Semirna Daniel, Fatma Gamal, Nada Saad, Hala Hamdy, Ghada Adel, Mahmoud Elnahas, Fady Wael, Sohair Aboelghar, Nada Hesham, Mohamed Tarek, and Hebatallah A. Wagdy

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Association Between COVID-19 Vaccination and Quality of Life Among University Students, Amani S. Elbarazi

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Childhood Maltreatment and its Mental Health Consequences among University's Students, Amani S. Elbarazi

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Cognitive Processing Therapy for the Treatment of PTSD, Depression, Anxiety Symptoms and Difficulties in Emotion Regulation in Syrian Refugee Women Exposed to Intimate Partner Violence, Amani S. Elbarazi

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How Social Media Affects People’s Ideas on Sexist Behaviours and Gender-Based Violence, Amani S. Elbarazi

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Psychological Support for Earthquake Survivors in Turkey and Syria, Amani S. Elbarazi

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The Association Between Compulsive Buying Disorder and Childhood Trauma, Amani S. Elbarazi

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Association between university student junk food consumption and mental health, Amani S. Elbarazi and Rajiv Tikamdas

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Intact Transition Epitope Mapping—Force Differences between Original and Unusual Residues (ITEM-FOUR), Reham F. El-Kased, Claudia Rower, Christian Ortmann, Andrei Neamtu, and Michael O. Glocker

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GC-MS profiling of Vitex pinnata bark lipophilic extract and screening of its anti-TB and cytotoxic activities, Dina M. El-Kersh, Safa Abdelbaset, Iriny M. Ayoub, and Omayma A. Eldahshan

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A Comprehensive Review on Grape Juice Beverage in Context to Its Processing and Composition with Future Perspectives to Maximize Its Value, Dina M. El-Kersh, Ghada Hammad, Marwa S. Donia, and Mohamed A. Farag

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Comparative MS- and NMR-Based Metabolome Mapping of Egyptian Red and White Squill Bulbs F. Liliaceae and in Relation to Their Cytotoxic Effect, Dina M. El-Kersh, Omar Khattab, Shaden A. M. Khalifa, Nermeen Yosri, Hesham R. El-Seedi, and Mohamed A. Farag

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Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic, and histopathological analyses, Dina M. El-Kersh; soheir E. Kotb; Naglaa M. Ammar,; Ola A.M. Mohawed; Hanaa H. Ahmed; and Mohamed Farag

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Potential antimicrobial and antibiofilm efficacy of essential oil nanoemulsion loadedpolycaprolactone nanofibrous dermal patches, Abdullah A.Y. Gibriel, M El-Naggar, A Abdelgawad, R Abdel-Sattar, and H Bahaa

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Rhamnetin ameliorates non-alcoholic steatosis and hepatocellular carcinoma in vitro, Abdullah A.Y. Gibriel, M Shatta, M Omar, and H El-Mesallamy

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Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes, Andrew Hakeem, Mohamed M. Kamal, Rasha A. Radwan, Basma A. AbdelRahman, Olfat A. Hammam, Mohey M. Elmazar, Aiman S. El-Khatib, and Yasmeen M. Attia

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Links between Integrin αvΒ3 and COVID-19: Impact on Vascular and Thrombotic Risk, Marwa Hamza and Shaker Mousa

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MitoQ alleviates hippocampal damage after cerebral ischemia: The potential role of SIRT6 in regulating mitochondrial dysfunction and neuroinflammation, Ayman A. Ibrahim, Sherif S. Abdel Mageed Dr, Marwa M. Safar Prof.Dr, Mohammed F. El-Yamany Prof.Dr., and Mamdouh A. Oraby Dr.

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Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer, Amira Khalil, Reham M. M. El Hazek, Nashwa H. Zaher, Hagar E. S. Emam, and Marwa G. Elgazzar

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Isatin-pyrimidine hybrid derivatives as enoyl acyl carrier protein reductase (InhA) inhibitors against Mycobacterium tuberculosis, Amira Khalil, Samy Mohamady, Amgad Albohy, Marwa M. Abdel-Aziz, and Abdalrahman Khalifa

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Challenging breast cancer through novel sulfonamide–pyridine hybrids: design, synthesis, carbonic anhydrase IX inhibition and induction of apoptosis., Amira Khalil, Nashwa H. Zaher, Reham MM Elhazek, Ahmed E. Gouda, and Marwa G. Elgazzar

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Size-optimized simvastatin-loaded TPGS modified lipid nanocapsules for targeting epithelial-to-mesenchymal transition in hepatocellular carcinoma: Role of PTEN/AKT signaling, Khaled Mahmoud, Mahmoud Teaima, Yasmeen Attiaa, Mohamed El-Nabarawi, and Shady Swidan

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Modulation of TLR4/NF-κB, Nrf2/HO-1 and PI3K/Akt signaling by cilostazol mitigates lipopolysaccharide-induced septic acute kidney injury, Ahmed F. Mohamed Dr., Helmy Said Dr, Hala F. Zaki, and Marwa M. Safar Prof. Dr.

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Modulation of TLR4/NF- Modulation of TLR4/NF-κB, Nrf2/HO-1 and PI3K/Akt signaling by cilostazol mitigates lipopolysaccharide-induced septic acute kidney injury, Ahmed F. Mohamed, Helmy M. Sayed, Hala F. Zaki, and Marwa Safar

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Development and validation of molnupiravir assessment in bulk powder and pharmaceutical formulation by the RP-HPLC-UV method, Ekram Hany Mohamed; A. H. Abdel Aziz; Noha M. El Zahar,; Nour El-Din A. Abdel-Sattar; Safwat A. Mahmoud,; and Mohamed S. Attia,

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Nanoghosts for therapeutic applications, Ekram Hany Mohamed, Abdel-Mottaleb, and Mohamed S. S. Attia

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Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis, Ekram Hany Mohamed; Mahmoud Tareq Abdelwahed,; and Maha A. Hegazy

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Highly selective optical sensor N/S-doped carbon quantum dots (CQDs) for the assessment of human chorionic gonadotropin β-hCG in the serum of breast and prostate cancer patients, Ekram Hany Mohamed; Yasmeen M. AlZahrani; Hind A. AlGhamdi,; Salha Alharthi; Mohamed S. S. Attia; Ahmed O. Youssef; Shahenda S. Ahmed; and Safwat A. Mahmoud,

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A highly selective optical sensor Eu-BINAM for assessment of high sensitivity cardiac troponin tumor marker in serum of cancer patients, Ekram Hany Mohamed, Mohamed S. Attia, Ahmed O. Youssef, and Shahenda S. Ahmed

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Development of potent nanosized carbonic anhydrase inhibitor for targeted therapy of hypoxic solid tumors, Ekram Hany Mohamed; Wagdy M. Eldehna,; Mahmoud A. El Hassab; and Nahla A. Abdelshafi,

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Environmentally sustainable computationally spectrophotometric resolution strategy for analysis single-tablet regimens of antihypertension with overlapped spectra, Ekram Hany Mohamed; Hayam M. Lotfy; and Reem H. Obaydo,

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Fabrication of novel electropolymerized conductive polymer of hydrophobic perfluorinated aniline as transducer layer on glassy carbon electrode: application to midazolam as a model drug of benzodiazepines, Ekram Hany Mohamed; Amr Mahmoud,; , Nancy Nashat; and Sally El-Mosallamy

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Unroasted Green Coffee Extract-Loaded Solid Lipid Nanoparticles for Enhancing Intestinal Permeation, Yomna Moussa, Mahmoud Teaima, Mohey Elmazar, Dalia Attia, and Mohamed El-Nabarawi

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Univariate and Multivariate Determination of Dapagliflozin and Saxagliptin in Bulk and Dosage Form, Shereen Mowaka, Manar M. Elhassan, Amr M. Mahmoud, and Maha A. Hegazy

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The potential off-target neuroprotective effect of sister gliflozins suggests their repurposing despite not crossing the blood–brain barrier: From bioanalytical assay in rats into theory genesis, Shereen Mowaka, Moataz S. Hendy, Ehab F. Elkady, Asmaa El-Zaher, and Bassam M. Ayoub

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DEVELOPMENT OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF NEBIVOLOL HYDROCHLORIDE, VALSARTAN AND HYDROCHLOROTHIAZIDE IN CO-ADMINISTRATED ANTIHYPERTENSIVE AGENTS AND HUMAN PLASMA, Shereen Mowaka, M. Rizk, Maha M. Abou El‐Alamin, and Mariam Mohamed

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Development, Optimization, and In Vitro/In Vivo Evaluation of Azelaic Acid Transethosomal Gel for Antidermatophyte Activity, Ali Nasr, Noha Badawi, Yasmine Tartor, Nader Sobhy, and Ali Nasr

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Hydroxysafflor yellow A protects against thioacetamide-induced liver fibrosis in rats via suppressing proinflammatory/fibrogenic mediators and promoting hepatic stellate cell senescence and apoptosis, Sayed H. Seif el-Din Dr., Olfat A. Hammam Dr, Shahira M. Ezzat Dr, Samira Saleh Prof.Dr., Marwa M. Safa Dr., Walaa H. ElMaadawy Dr, and Naglaa M. El-Lakkany Dr.

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Polymorphic renal transporters and cisplatin's toxicity in urinary bladder cancer patients: current perspectives and future directions, Mohamed S. Selim, Amira Kassem, Noha El‑Bassiouny, Ahmad Salahuddin, Raghda Abu El‑Ela, and Marwa Hamza

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Fabrication and characterization of anti-rosacea 3D nanofibrous customized sheet masks as a novel scaffold for repurposed use of spironolactone with pre-clinical studies, Shady Swidan, Nahla A. Elhesaisy, Rasha A. Tawfiq, Mohamed El-Nabarawi, and Mahmoud Teaima

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Characterization, antibacterial, antioxidant, antidiabetic, and anti-inflammatory activities of green synthesized silver nanoparticles using Phragmanthera austroarabica A. G. Mill and J. A. Nyberg extract, Shady Swidan, Dina Khodeer, Sarah Shabayek, Ali Nasr, Roaa Khinkar, Mohammed Aldurdunji, Maryam Ramadan, and Jihan Badr

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Exploring the potential of intranasally administered naturally occurring quercetin loaded into polymeric nanocapsules as a novel platform for the treatment of anxiety, Shady Swidan, Khaled Younis Mahmoud, Nahla Ahmed Elhesaisy, Abdelrahman Rashed, Ebram Mikhael, Mahmoud Fadl, Mahmoud Elsadek, Merna Mohamed, Merna Mostafa, Mohamed Hassan, Omar Halema, and Youssef Elnemer

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Design of experiment-based green UPLC-DAD method for the simultaneous determination of indacaterol, glycopyrronium and mometasone in their combined dosage form and spiked human plasma, Mohamed Tarek, Nermine S. Ghoniem, Maha A. Hegazy, and Hebatallah Wagdy

Submissions from 2022

Antioxidant-biocompatible and stable catalase-based gelatin-alginate hydrogel scaffold with thermal wound healing capability: immobilization and delivery approach, Heidi Mohamed Abdel-Mageed, Amira Emad Abd El Aziz, Batoul Mohamed Abdel Raouf, Saleh Ahmed Mohamed, and Dina Nada

Optimization of catalytic properties of Mucor racemosus lipase through immobilization in a biocompatible alginate gelatin hydrogel matrix for free fatty acid production: a sustainable robust biocatalyst for ultrasound-assisted olive oil hydrolysis, Heidi Mohamed Abdel-Mageed, Dina Nada, Rasha Ali Radwan, Saleh Ahmed Mohamed, and Nesrine Abdelrehim E L Gohary

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2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights, Amgad Albohy

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2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights, Amgad Albohy

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Anti-Inflammatory, Antiallergic and COVID-19 Main Protease (Mpro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus costaricaensis, Amgad Albohy

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Antiulcer Potential of Psidium guajava Seed Extract Supported by Metabolic Profiling and Molecular Docking, Amgad Albohy

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Biodiversity of N-acyl homoserine lactonase (aiiA) gene from Bacillus subtilis, Amgad Albohy

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Evaluation of antiviral activity of Carica papaya leaves against SARS-CoV-2 assisted by metabolomic profiling, Amgad Albohy

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Identifying the specific-targeted marine cerebrosides against SARS-CoV-2: An integrated computational approach, Amgad Albohy

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Metabolomic profiling of three Araucaria species, and their possible potential role against COVID-19, Amgad Albohy

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Multitarget in silico studies of Ocimum menthiifolium, family Lamiaceae against SARSCoV- 2 supported by molecular dynamics simulation, Amgad Albohy

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Neuroprotective repositioning and anti-tau effect of carvedilol on rotenone induced neurotoxicity in rats: Insights from an insilico& in vivo (InhA) inhibitors against Mycobacterium tuberculosis, Amgad Albohy

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Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights, Amgad Albohy

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Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades, Amgad Albohy

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Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity, Amgad Albohy

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Remdesivir analog as SARS-CoV-2 polymerase inhibitor: virtual screening of a database generated by scaffold replacement, Amgad Albohy, Mohamed A. Said, Mohamed A. Abdelrahman, and Hany Said

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Selective Engram Coreactivation In Idling Brain Inspires Implicit Learning, Mohamed H. Aly, Kareem Abdou, Reiko Okubo-Suzuki, Masanori Nomoto, and Kaoru Inokuchi

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Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome, Reham A. Ammar, Ahmed F. Mohamed, Mohamed M. Kamal, Marwa M. Safar, and Noha F. Abdelkader

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Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study, Dalia Attia, Caroline Lamie, Enas Elmowafy, Maha Ragaie, and Nahed Mortada

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Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors?, Dalia Attia; Caroline Lamie; Nahed Mortada; Mohey El-Mazar; and Enas Elmowafy,

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Screening of Adapalene Microsponges Fabrication Parameters with Insight on the In vitro Biological Effectiveness, Dalia Attia, Rania M Yehia, Mohey Elmazar, Mohamed A El-Nabarawi, and Mahmoud H Teaima

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Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma, Dalia Attia, Mahmoud Teaima, Noha Badawi, Mohamed El-Nabarawi, mohamed Elmazar, and Shaker Mousa

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Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery, Yasmeen M. Attia, Mustafa Maher, Olfat Hammam, Soheir Mahmoud, Wafaa Kandil, and Mohamed Salah

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Obeticholic acid orchestrates the crosstalk between ileal autophagy and tight junctions in non-alcoholic steatohepatitis: Role of TLR4/TGF-β1 axis, Yasmeen M. Attia, Rasha Tawfiq, Noha Nassar, Dalaal Abdallah, Olfat Hammam, Rasha Allam, and Mohamed Elmazar

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Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer, Noha Badawi, Yasmeen M. Attia, Dina M. El-Kersh, Olfat A. Hammam, and Maha KA Khalifa

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POST-TRAUMATIC STRESS DISORDER AND DIFFICULTIES IN EMOTION REGULATION AMONG UNIVERSITY STUDENTS UNDER THE COVID-19 CONDITION, Amani S. Elbarazi

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Supporting Women to Heal from Trauma and Post-Traumatic Stress Disorder, Amani S. Elbarazi and Salma Ahmed

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COGNITIVE PROCESSING THERAPY VERSUS MEDICATION FOR THE TREATMENT OF COMORBID SUBSTANCE USE DISORDER AND POST-TRAUMATIC STRESS DISORDER IN EGYPTIAN PATIENTS (RANDOMIZED CLINICAL TRIAL), Amani S. Elbarazi, Osama Badary, Mohey Elmazar, and Hanan Elrasas

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The Management of Social Anxiety: More Than 25 Years Later, Where are we?, Amani S. Elbarazi and Pierre Meshreky

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Cognitive Processing Therapy for the Treatment of PTSD, Depression and Anxiety in Syrian Refugees in Egypt, Amani S. Elbarazi, Rajiv Tikamdas, Salma Ahmed, and Salma Ramadan

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Characterization and anti-biofilm activity of bacteriophages against urinary tract Enterococcus faecalis isolates, Reham F. El-Kased, Doaa M. El-Atrees, Ahmad M. Abbas, and Mahmoud A. Yassien

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GC–MS Profiling of Naturally Extracted Essential Oils: Antimicrobial and Beverage Preservative Actions, Reham F. El-Kased and Dina M. El-Kersh

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Antioxidant, Antimicrobial Activities and Characterization of Polyphenol-Enriched Extract of Egyptian Celery (Apium graveolens L., Apiaceae) Aerial Parts via UPLC/ESI/TOF-MS, Reham F. El-Kased, Dalia M. Rasheed, Ayat M. Emad, and Dina M. El-Kersh

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Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking, Dina M. El-Kersh, Rania Abou El-Ezz, Marwa Fouad, and Mohamed Farag

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Natural acylated flavonoids: their chemistry and biological merits in context to molecular docking studies, Dina M. El-Kersh, Ahmed Essa, Mohamed Teleb, Abd El-Nasser G. El Gendy, Abdelsamed Elshamy, and Mohamed Farag

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Apple Pomace as a Source of Nutraceuticals, Dina M. El-Kersh, Shahira Ezzat, Maha M. Salama, and Mohamed Salem

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Unveiling major ethnopharmacological aspects of genus Diospyros in context to its chemical diversity: A comprehensive overview, Dina M. El-Kersh, Rola M. Labib, Fadia S. Youssef, and nada fareed

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GC-MS metabolites profiling of anethole-rich oils by different extraction techniques: antioxidant, cytotoxicity and in-silico enzymes inhibitory insights, Dina M. El-Kersh, Nada Mostafa, Shaimaa Fayez, Tarfah Al-Warhi, Mohammed Abourehab, Wagdy Eldehna, and Mohamed Salem

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GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study, Dina M. El-Kersh, Chandan Sarkar, Mondal Milon, Khattab Al-Khafaji, Sarmin Jamaddar, Pranta Ray, Uttam Kumar Roy, Mirola Afroze, Md. Moniruzzaman, Mala Khan, Umma Hafsa Asha, and Abul Bashar Ripon Khalipha

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Diagnosis and staging of HCV associated fibrosis, cirrhosis and hepatocellular carcinoma with target identification for miR-650, 552-3p, 676-3p, 512-5p and 147b, Abdullah A.Y. Gibriel, M ISMAIL, H SLEEM, N ZAYED, A YOSRY, S EL-NAHAAS, and N SHEHATA